The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved $70 million for nine new patient-centered research projects focused on conditions ranging from ductal carcinoma in situ (DCIS), a very early stage, localized type of breast cancer to diabetes, chronic lung disease, and migraines.
The Patient-Centered Outcomes Research Institute (PCORI) and the American Heart Association (AHA) will announce today a new joint initiative that will combine the outreach power of crowdsourcing with the lure of challenge prizes to speed the identification of critical research needed to improve care for cardiovascular diseases (CVD).
PCORI welcomes you to learn more about research we fund, our programs and initiatives. In an effort to better understand our work, we have provided a list of fact sheets below that are available for you to download and print.
Research Done Differently
Better Research Through Engagement
PCORI's Pragmatic Clinical Studies Initiative
PCORnet - the National Patient-Centered Clinical Research Network
PCORnet’s First Observational Studies
The PCORnet ADAPTABLE Aspirin Study
Snapshots of PCORI Research on Specific Topics
PCORI-Funded Research on Addressing Healthcare Disparities
PCORI-Funded Research on Cancer
PCORI-Funded Research on Cardiovascular Disease
PCORI-Funded Research on Chronic Pain and Opioids
PCORI-Funded Research on Dementia and Cognitive Impairment
PCORI-Funded Research on Mental Health
Funded Research Snapshots
The PCORI Application Process
Help Wanted - PCORI Reviewers
Why Methods Matter
Posted: September 30, 2014; Updated: January 15, 2016
This collection of articles and opinion pieces provides insights into PCORI’s work to advance patient-centered comparative clinical effectiveness research. The collection includes papers, articles, and commentaries written by researchers working on PCORI-funded projects and by PCORI staff, members of our Board of Governors and Methodology Committee, and others who are following our work.
PCORI is committed to the principle of transparency and openness in all of our work, including the sharing of information about our activities and the dissemination of research findings. We encourage authors to make their articles available without a subscription. In the list below, we provide links when articles are available without charge.
Papers Resulting from PCORI-Funded Research Studies
Thackeray J, Minneci PC, Cooper JN, Groner JI, Deans KJ. Predictors of increasing injury severity across suspected recurrent episodes of non-accidental trauma: a retrospective cohort study. BMC Pediatr. 2016 Jan 16;16(1):8. doi:10.1186/s12887-016-0540-y. PubMed PMID: 26772185; PubMed Central PMCID: PMC4715331.
View PCORI Study
Journal of Advanced Nursing
Tubbs-Cooley HL, Pickler RH, Simmons JM, Auger KA, Beck AF, Sauers-Ford HS, Sucharew H, Solan LG, White CM, Sherman SN, Statile AM, Shah SS; H2O Study Group. Testing a post-discharge nurse-led transitional home visit in acute care pediatrics: the Hospital-To-Home Outcomes (H2O) study protocol. J Adv Nurs. 2016 Jan 28. doi: 10.1111/jan.12882. [Epub ahead of print] PubMed PMID: 26817441. (Abstract only available)
View PCORI Study
Journal of Comparative Effectiveness Research
Erwin K, Krishnan JA. Using design methods to provide the care that people want and need. J Comp Eff Res. 2016 Jan;5(1):13-5. doi: 10.2217/cer.15.62. PubMed PMID: 26698828.
View PCORI Study
Erwin K, Martin MA, Flippin T, Norell S, Shadlyn A, Yang J, Falco P, Rivera J, Ignoffo S, Kumar R, Margellos-Anast H, McDermott M, McMahon K, Mosnaim G, Nyenhuis SM, Press VG, Ramsay JE, Soyemi K, Thompson TM, Krishnan JA. Engaging stakeholders to design a comparative effectiveness trial in children with uncontrolled asthma. J Comp Eff Res. 2016 Jan;5(1):17-30. doi: 10.2217/cer.15.52. Epub 2015 Dec 21. PubMed PMID: 26690579.
View PCORI Study
Journal of Thoracic Oncology
Osarogiagbon RU, Lin CC, Smeltzer MP, Jemal A. Prevalence, Prognostic Implications, and Survival Modulators of Incompletely Resected Non-Small Cell Lung Cancer in the U.S. National Cancer Data Base. J Thorac Oncol. 2016 Jan;11(1):e5-e16. doi: 10.1016/j.jtho.2015.08.002. PubMed PMID: 26762752; PubMed Central PMCID: PMC4714753. (Abstract only available)
View PCORI Study
Papers Authored by PCORI Staff and Leadership
Stakeholder-Driven Comparative Effectiveness Research: An Update From PCORI
Joseph V. Selby, Laura Forsythe, Harold C. Sox, "Stakeholder-Driven Comparative Effectiveness Research: An Update From PCORI," Journal of the American Medical Association (November 2015).
The Rationale for Patient-Reported Outcomes Surveillance in Cancer and a Reproducible Method for Achieving It (Abstract only available)
T.G. Smith, K.M. Castro, A.N. Troeschel, N.K. Arora et al., "The Rationale for Patient-Reported Outcomes Surveillance in Cancer and a Reproducible Method for Achieving It," Cancer (November 2015).
Patient and Stakeholder Engagement in the PCORI Pilot Projects: Description and Lessons Learned
Laura P. Forsythe, Lauren E. Ellis, Lauren Edmundson, Raj Sabharwal, Alison Rein, Kristen Konopka, Lori Frank, "Patient and Stakeholder Engagement in the PCORI Pilot Projects: Description and Lessons Learned," Journal of General Internal Medicine (July 2015).
Patient and Clinician Views on Comparative Effectiveness Research and Engagement in Research
Laura Forsythe, Lori Frank, Kara Odom-Walker, Ayodola Anise et al., "Patient and Clinician Views on Comparative Effectiveness Research and Engagement in Research," Journal of Comparative Effectiveness Research 4(1) (January 2015): 11-25.
Other Papers on PCORI's Work
Model for a Patient‐Centered Comparative Effectiveness Research Center
Monica R. Costlow, Douglas P. Landsittel et al., 'Model for a Patient‐Centered Comparative Effectiveness Research Center," Clinical and Translational Science (January 2015): DOI: 10.1111/cts.12257.
Building a Career as a Delivery Science Researcher in a Changing Health Care Landscape
Richard W. Grant and Julie A. Schmittdiel, "Building a Career as a Delivery Science Researcher in a Changing Health Care Landscape," Journal of General Internal Medicine (January 2015).
The Role of Technical Advances in the Adoption and Integration of Patient-reported Outcomes in Clinical Care
Roxanne E. Jensen, Nan E. Rothrock, Esi M. DeWitt et al., "The Role of Technical Advances in the Adoption and Integration of Patient-reported Outcomes in Clinical Care," Medical Care 53(2) (February 2015): 153-159.
US Big-data Health Network Launches Aspirin Study: PCORI Clinical-research Initiative Will Collect Information on Some 30 Million People
Sara Reardon, "US Big-data Health Network Launches Aspirin Study: PCORI Clinical-research Initiative Will Collect Information on Some 30 Million People," Nature 512(7512) (August 2014).
Posted: March 5, 2014; Updated: February 3, 2016