Research Methodology

Developing and improving the science and methods of patient-centered outcomes research (PCOR) is a central part of PCORI’s work. Better methods will produce more valid, trustworthy, and useful information that will lead to better healthcare decisions, and ultimately to improved patient outcomes.

Robin Newhouse Video ScreenshotMethodology Standards

PCORI’s Methodology Committee, in accordance with PCORI’s authorizing legislation, submitted to the Board of Governors on May 10, 2012, the first draft PCORI Methodology Report. After a 54-day public comment period, the report’s draft Methodology Standards were revised and adopted by the Board on November 19, 2012, then published on December 14, 2012. At its November 18, 2013 meeting, the Board of Governors approved minor editorial revisions to the standards.  See the standards here.

PCORI considers the accomplishment of developing, refining, and finalizing these standards to be a critical step in advancing the field of PCOR. We look forward to working with our many stakeholders to see that these standards become a useful and valued resource for the entire healthcare community.

Proposed studies are required to adhere to relevant PCORI methodology standards as published in December 2012. If a proposed study uses an approach or elements not covered by those standards, it should adhere to other current accepted best practices.  A variety of study designs and analytic methods may contribute valid new knowledge.

Methodology Report

During its November 18, 2013 meeting, PCORI’s Board of Governors accepted the report presented by PCORI’s Methodology Committee, which was revised to address extensive feedback received from the healthcare community during a public comment period that followed the July 2012 release of a draft. To view the revised report and its appendixes, click on the titles below:

Draft Report and background materials:

Articles of Interest


Posted September 21, 2013; Updated December 5, 2013