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PCORI

Patient-Centered Outcomes Research Institute

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    About Us

    • Our Programs
    • Governance
    • Financials and Reports
    • Procurement Opportunities
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    Subscribe to PCORI Email Alerts

    Sign up for weekly emails to stay current on the latest results of our funded projects, and more.

    Learn More About PCORI

    Download fact sheets about our work, the research we fund, and our programs and initiatives.

    Join Us! Work at PCORI

    View our current openings, benefits and apply online. Featured Opening: Program Officer

  • Research & Results
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    Research & Results

    • Explore Our Portfolio
    • Research Results Highlights
    • PCORI in the Literature
    • Putting Evidence to Work
    • Peer Review
    • Evidence Synthesis
    • About Our Research

    Highlights of PCORI-Funded Research Results

    Read about results that are being published in leading medical journals and presented at major scientific meetings.

    CE/CME Activities: Treatment Options After a Stroke

    Find out how to apply research findings to help patients with atrial fibrillation make informed decisions about treatments following an ischemic stroke.

    Explore Our Portfolio of Funded Projects

    Find out about projects based on the health conditions they focus on, the state they are in, and if they have results.

  • Topics
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    Topics

    • Addressing Disparities
    • Cancer
    • Cardiovascular Disease
    • Community Health Workers
    • Dementia and Cognitive Impairment
    • Diabetes
    • Kidney Disease
    • Mental and Behavioral Health
    • Multiple Chronic Conditions
    • Multiple Sclerosis
    • Obesity
    • Older Adults' Health
    • Pain Care and Opioids
    • Rare Diseases
    • Shared Decision Making
    • Telehealth
    • Transitional Care

    Featured Topic: Multiple Chronic Conditions

    A PCORI-funded study shows that a family-centered communication program in pediatric departments directly improves hospital safety.

  • Engagement
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    Engagement

    • The Value of Engagement
    • Engagement in Health Research Literature Explorer
    • Influencing the Culture of Research
    • Engagement Awards
    • Engagement Resources
    • Engage with Us

    Older Adults Advise Researchers

    An Engagement Award brings together researchers and older adults living at home and in skilled nursing facilities to improve older adults' care.

    Explore Engagement in Health Literature

    PCORI has developed a new tool that enables searching for published articles about engagement in health research.

    Using the PCORI Engagement Rubric

    It provides general guidance and suggestions for engagement compliance and engagement strategies in the research process.

  • Funding Opportunities
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    Funding Opportunities

    • What & Who We Fund
    • What You Need to Know to Apply
    • Applicant Training
    • Merit Review Process
    • Awardee Resources
    • Help Center

    PCORI Funding Announcements

    Learn about open and upcoming funding announcements and how to apply.

    Tips for Submitting a Responsive LOI

    Find out what PCORI looks for in a letter of intent (LOI) along with other helpful tips.

    Do You Have Questions?

    PCORI's Help Center includes an FAQ section for answers to applicant, awardee and reviewer questions.

  • Meetings & Events
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    Meetings & Events

    • Upcoming
    • Past Events

    Watch Our Facebook Live Discussion

    We discussed how telehealth might help improve the outcomes for patients living with serious mental illness.

    Hear from PCORI Staff

    Invite a PCORI staffer to talk about our work and see a schedule of our staffers' speaking engagements.

    From Evidence to Impact: Putting What Works into Action

    Watch archived recordings of our 2018 Annual Meeting's keynotes, plenaries and breakout sessions.

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  • About Us
  • Our Programs
  • Research Infrastructure

Research Infrastructure

Under the auspices of our Research Infrastructure program, we are creating a national network to foster a wide range of observational and experimental comparative clinical effectiveness research (CER) studies. This network, known as PCORnet, the National Patient-Centered Clinical Research Network, is designed to find a faster, less expensive, more powerful way to conduct CER to improve the nation’s health and health care.

This “network of networks” can harness the power of large amounts of health information, including data from electronic health records, while taking advantage of strong partnerships between patients, clinicians, and health systems. Such a national network, guided by the wide range of healthcare stakeholders, enables researchers to efficiently address the real-world needs of patients and those who care for them.

This large infrastructure can support researchers conducting large observational studies that include clinical and patient-reported outcomes and also large, pragmatic clinical trials embedded within participating systems. The network is implementing streamlined contracting, data sharing, and Institution Review Board review protocols to increase efficiency.

The Research Infrastructure program funds and manages the 33 partner networks and a Coordinating Center that make up PCORnet. There are 13 Clinical Data Research Networks (CDRNs), based in healthcare systems such as hospitals, integrated delivery systems, and federally qualified health centers, and 20 Patient-Powered Research Networks (PPRNs), operated and governed by groups of patients and their partners focused on one or more specific conditions or communities, and interested in sharing health information and participating in research.

Several demonstration studies are under way to answer important questions while testing the technical capacity and function of the PCORnet’s infrastructure:

  • Patient-Powered Research Networks (PPRN) Research Demonstration Projects
  • Obesity Observational Research Initiative
  • Optimal Maintenance Aspirin Dose for Patients with Coronary Artery Disease
  • The Natural Experiments Network: A Collaborative Initiative

PCORnet also plans to increase network collaborations within PCORnet and with the wider research community. The Research Infrastructure program has championed demonstration projects to enhance network development and manages collaborations with federal partners.

Patients and other stakeholders are deeply involved in the development and implementation of network activities. When fully realized, PCORnet will improve the pace, quality, and patient-centered nature of clinical research.


Posted: February 25, 2016; Updated: April 7, 2017

About Us

  • Our Programs
  • Governance
  • Financials and Reports
  • Procurement Opportunities
  • Our Staff
  • Contact Us

Research & Results

  • Explore Our Portfolio
  • Research Results Highlights
  • PCORI in the Literature
  • Putting Evidence to Work
  • Peer Review
  • Evidence Synthesis
  • About Our Research

Engagement

  • The Value of Engagement
  • Engagement in Health Research Literature Explorer
  • Influencing the Culture of Research
  • Engagement Awards
  • Engagement Resources
  • Engage with Us

Funding Opportunities

  • What & Who We Fund
  • What You Need to Know to Apply
  • Applicant Training
  • Merit Review Process
  • Awardee Resources
  • Help Center

Meetings & Events

February 26
Board of Governors Meeting: February 26, 2019
March 19
Board of Governors Meeting: March 19, 2019
April 16
Board of Governors Meeting: April 16, 2019

PCORI

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Patient-Centered Outcomes
Research Institute

1828 L Street, NW, Suite 900
Washington, DC 20036
Phone: (202) 827-7700 | Fax: (202) 355-9558
info@pcori.org

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