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Patient-Centeredness for Treatment-Resistant Depression: Comparative Clinical Effectiveness Research Trial Tests a New Approach
Blog
Treatment-Resistant Depression Major depressive disorder is a serious health concern for adults in the United States. According to data from the Centers for Disease Control and Prevention, close to one…
Reaching the Summit: Patient-Centered CER Helps Women Overcome Peripartum Depression
Blog
What is peripartum depression? Peripartum depression is more than just “baby blues:” this condition is clinical depression experienced by a person during pregnancy or after giving birth that can continue…
PCORI approves $123 million for research on postpartum care, hypertension management, antibiotic prescribing and a range of conditions
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $123 million to support 15 new research studies. These studies aim to fill evidence gaps, enhance…
Spotlight on National Sickle Cell Disease Awareness Month
Blog
More than 100,000 people in the United States have sickle cell disease —a group of inherited red blood cell disorders that affect blood flow and the body’s use of oxygen…
PCORI approves $258 million to fund research studies addressing mental health, heart-related care, and a range of chronic and acute conditions
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling $258 million to support 26 new research studies. These studies aim to fill evidence gaps and…
Evidence Updates Highlight New Findings from PCORI-Funded Research
Blog
Conducting clinical research studies often takes years, from recruiting participants to analyzing data. It can often take many more years for new evidence from research to inform health care and…
PCORI Researchers Are Answering Rapidly Emerging Questions about Telehealth
Blog
Telehealth—the use of digital information and communication technologies, such as computers and mobile devices, to access health care services remotely and manage health care—has grown in promise as technology has…
Can Some MS Patients Safely Stop Taking Medicines?
Blog
Multiple sclerosis is an often disabling neurological condition that affects about 400,000 people in the United States. People with MS can develop a wide variety of symptoms, including vision problems…
Drawing on Mental Health "Experts-by-Experience"
Blog
An estimated 43.6 million American adults—nearly one in five—have mental illness. Anxiety and mood disorders, including depression, are the most common forms. While these conditions are usually treatable, clinicians often…
Taking the Confusion out of Breast Cancer Screening
Blog
At its core, screening for breast cancer aims to save lives. The idea is intuitively attractive: Find a tumor early, before the disease becomes more serious, and some combination of…
Mindfulness-Based Stress Reduction Just as Safe, Effective as Common Medication for Anxiety Disorders, Study Finds
Research Study Highlight
Adults with anxiety disorders can experience comparable relief from either meditation or a commonly prescribed medication, according to findings from a PCORI-funded study published in JAMA Psychiatry . For the…
ELEKT-D Study: Ketamine as Effective as ECT for Treating Major Depression
Research Study Highlight
An estimated one in three people with clinical depression do not respond to antidepressants, limiting their treatment option to electroconvulsive therapy (ECT), which has been linked to physical and mental…
Can Patients with MS Safely Stop Taking Medicine as They Age? DISCOMS Trial's Results Indicate It's a Reasonable Option for Some
Research Study Highlight
Although new results from an ongoing PCORI-funded study into whether some patients with multiple sclerosis (MS) can safely stop taking certain kinds of medications as they age weren’t conclusive in…
BeWeL Study: Award-Winning Video Seeks to Help Reduce Suicide Risk Among Alaska Native Young People
Research Study Highlight
September marks National Suicide Prevention Month, a time to raise awareness about suicide prevention and share messages of hope. Suicide is the leading cause of death among Alaska Native young…
TrACER Study: Changing Prescription Order Systems to Lower Risk of Febrile Neutropenia in Patients Starting Chemotherapy
Research Study Highlight
Some patients who receive chemotherapy develop a serious health problem called febrile neutropenia (FN), which involves having a fever and a low number of a type of white blood cells…
