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Patient-Centeredness for Treatment-Resistant Depression: Comparative Clinical Effectiveness Research Trial Tests a New Approach
Blog
Treatment-Resistant Depression Major depressive disorder is a serious health concern for adults in the United States. According to data from the Centers for Disease Control and Prevention, close to one…
Reaching the Summit: Patient-Centered CER Helps Women Overcome Peripartum Depression
Blog
What is peripartum depression? Peripartum depression is more than just “baby blues:” this condition is clinical depression experienced by a person during pregnancy or after giving birth that can continue…
Engagement Award October 2023 Cycle Funding Announcements Open
Blog
The Eugene Washington PCORI Engagement Award Program is now accepting applications for the October 2023 Cycle PCORI Funding Announcements (PFAs). The Engagement Award Program supports projects that encourage active, meaningful…
PCORI to direct up to $600 million in health research funding spanning eight high-need areas impacting the nation's health
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved PCORI investing up to $600 million in patient-centered comparative clinical effectiveness research (CER) through the development…
PCORI offers up to $452 million through new health research funding opportunities on various topics
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today began inviting proposals for new studies and implementation projects through nine funding opportunities. These PCORI Funding Announcements (PFAs) include four…
PCORI approves $123 million for research on postpartum care, hypertension management, antibiotic prescribing and a range of conditions
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $123 million to support 15 new research studies. These studies aim to fill evidence gaps, enhance…
PCORI offers up to $308.5 million through new funding opportunities
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has opened the application periods for nine funding opportunities that offer up to $308.5 million in total funding. The latest PCORI…
Annual Meeting Highlights Essential PCORI Values
Leadership Perspective
The eighth PCORI Annual Meeting last month highlighted so much of what makes our community special: a broad, diverse range of engaged stakeholders; inspirational expert speakers; compelling results from patient-centered…
Topic Themes: Informing Future PCORI Funding Opportunities
Blog
Editor's Note (February 27, 2023) These eight Topic Themes join four that are ongoing—preventing maternal morbidity and mortality, improving outcomes for people with intellectual or developmental disabilities, addressing COVID-19, and…
PCORI Annual Meeting Keynote Speaker -- Co-Founder and President of Sick Cells -- Continues to Honor her Late Brother's Vision
Blog
Every day of the year, and not just during National Sickle Cell Awareness Month, Ashley Valentine, co-founder, and president of Sick Cells , celebrates the legacy of her late brother…
MEDIA ADVISORY: Health equity, COVID-19 research headline PCORI’s 2022 Annual Meeting October 26-27
News Release
WASHINGTON, D.C. — Registration is now open for the Patient-Centered Outcomes Research Institute (PCORI)’s 2022 Annual Meeting , a free, virtual event running October 26-27 that brings together patients and…
Spotlight on National Sickle Cell Disease Awareness Month
Blog
More than 100,000 people in the United States have sickle cell disease —a group of inherited red blood cell disorders that affect blood flow and the body’s use of oxygen…
PCORI approves $258 million to fund research studies addressing mental health, heart-related care, and a range of chronic and acute conditions
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling $258 million to support 26 new research studies. These studies aim to fill evidence gaps and…
Evidence Updates Highlight New Findings from PCORI-Funded Research
Blog
Conducting clinical research studies often takes years, from recruiting participants to analyzing data. It can often take many more years for new evidence from research to inform health care and…
PCORI Board approves 28 new members to advisory panels
News Release
The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors yesterday approved proposed slates with a total of 28 people to serve on PCORI’s five multi-stakeholder advisory panels. Panelists were chosen from more than 150 candidates who either nominated themselves or were nominated by others. In addition, the Board approved the appointments of current advisory panel members to serve as chairs for three advisory panels.
PCORI-Funded Project Featured on Good Morning America Website
Blog
ABC News’ flagship morning program Good Morning America recently featured an online story on care for people with Down syndrome that highlighted a PCORI-funded project. The story about 28-year-old Cristina…
PCORI Researchers Are Answering Rapidly Emerging Questions about Telehealth
Blog
Telehealth—the use of digital information and communication technologies, such as computers and mobile devices, to access health care services remotely and manage health care—has grown in promise as technology has…
COVID-19, Other Research Funding Opportunities Open for Proposals
Blog
As COVID-19 continues to present unique healthcare challenges to our nation, PCORI in turn continues to consider how we can best contribute to ongoing efforts to combat it hand in…
PCORI's Continued Commitment to Researching Rare Diseases
Blog
It’s been an eventful year for Scott Berns, MD, MPH. In 2019, Berns and his wife, Leslie Gordon, MD, PhD, were keynote speakers at the PCORI Annual Meeting. Then, in…
How I Cured My Rare Disease
Blog
Editor's Note: The views expressed here are those of the author and not necessarily those of PCORI. There are an estimated 25 to 30 million rare disease sufferers in the…
Can Some MS Patients Safely Stop Taking Medicines?
Blog
Multiple sclerosis is an often disabling neurological condition that affects about 400,000 people in the United States. People with MS can develop a wide variety of symptoms, including vision problems…
Drawing on Mental Health "Experts-by-Experience"
Blog
An estimated 43.6 million American adults—nearly one in five—have mental illness. Anxiety and mood disorders, including depression, are the most common forms. While these conditions are usually treatable, clinicians often…
How Patient-Centered Outcomes Research Helps Families With Rare Diseases
Blog
Despite the name, "rare diseases" affect 30 million Americans. And their impact is severe—some of these illnesses have no effective treatment, and many are debilitating and life threatening. Yet each…
The COMBINE TRIAL: Improving Treatment for Pediatric Crohn's Disease
Research Study Highlight
Pediatric patients receiving the tumor necrosis factor (TNF) inhibitor adalimumab, combined with a low dose of methotrexate, a second immunosuppressant, to treat Crohn’s disease did better than those treated with…
New Research Funding Opportunities on Addressing Rare Diseases, Substance Use, and Other Topics Open May 7
Funding Announcement Notice
PCORI's Online System will open on May 7, 2024, for the submission of Letters of Intent (LOI) for several research PCORI Funding Announcements (PFA), which will fund proposals for high-quality…