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WASHINGTON, D.C. — The Patient-Centered Outcomes Research Institute (PCORI) today announced the approval of funding awards totaling more than $150 million to support new patient-centered comparative clinical effectiveness research (CER)…

Colon Cancer Screening for Older Adults For adults ages 45 to 75, it is recommended to do routine screening for colorectal cancer — also called colon cancer — or for…

PCORI’s mandate is to improve the quality and relevance of evidence that can help patients, caregivers, clinicians and others make better-informed health or healthcare decisions. Our Evidence Updates are one…

WASHINGTON, D.C. — The Patient-Centered Outcomes Research Institute (PCORI) today began inviting proposals for new studies and projects through 10 funding opportunities. Five of these PCORI Funding Announcements (PFAs) are…

WASHINGTON, D.C. — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $80.5 million to support four new, ambitious patient-centered comparative clinical effectiveness research (CER) studies focused on…

WASHINGTON, D.C. — The Patient-Centered Outcomes Research Institute (PCORI) today announced the approval of funding awards totaling $225 million, which include $207 million to support 20 new patient-centered comparative clinical…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $208 million to support 17 new comparative clinical effectiveness research (CER) studies, including four trials of…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $123 million to support 15 new research studies. These studies aim to fill evidence gaps, enhance…

More than 100,000 people in the United States have sickle cell disease —a group of inherited red blood cell disorders that affect blood flow and the body’s use of oxygen…

The COVID-19 pandemic triggered many uncertainties and concerns for pregnant people, who were faced with navigating frequent prenatal and postpartum healthcare visits under risk of COVID-19 exposure. The pandemic has…

Our efforts to engage patients and stakeholders across the healthcare community, and focus on outcomes of interest to patients and those who care for them, are how we conduct Research…

A Eugene Washington PCORI Engagement Award project’s location plays a distinct role in its planning and implementation. For example, rural populations and people living in low-income and historically underserved areas…

WASHINGTON, DC—The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved an award slate with $32.7 million for a large, multi-phase comparative clinical effectiveness research (CER) study to compare…

Every time a parent leaves our neonatal intensive care unit (NICU) to take their child home, we are asking them to do superhuman things. At Children’s National Hospital, the tasks…

It is devastating for anyone to lose somebody, especially when that person is a child. When my young, twin daughter received the diagnosis of stage IV neuroblastoma, a cancer of…

Telehealth—the use of digital information and communication technologies, such as computers and mobile devices, to access health care services remotely and manage health care—has grown in promise as technology has…

Mental health is a topic that some people feel uncomfortable discussing. But failing to spread mental health awareness can have serious consequences. For example, people with serious mental illness (SMI)—conditions…

An estimated 43.6 million American adults—nearly one in five—have mental illness. Anxiety and mood disorders, including depression, are the most common forms. While these conditions are usually treatable, clinicians often…

At its core, screening for breast cancer aims to save lives. The idea is intuitively attractive: Find a tumor early, before the disease becomes more serious, and some combination of…

Adults with cancer who took a newer oral blood thinner to prevent recurrent venous thromboembolism (VTE), or blood clots, fared just as well as those who took an older injectable…

Adults with anxiety disorders can experience comparable relief from either meditation or a commonly prescribed medication, according to findings from a PCORI-funded study published in JAMA Psychiatry . For the…

For older adults, guidelines recommend clinicians and patients work together to make decisions about colorectal cancer screening (CRC). However, these conversations must consider several factors and can be challenging. The…

Patients with advanced cancer who used telehealth to regularly report symptoms improved their overall well-being, compared with those who were seen less frequently via in-person clinical visits, according to results…

Some patients who receive chemotherapy develop a serious health problem called febrile neutropenia (FN), which involves having a fever and a low number of a type of white blood cells…

The latest Emerging Health Care Innovation Brief looks at a few high-profile weight loss drugs that have received renewed attention with a recent policy decision that could expand their use…