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Testing Approaches for Deciding to Screen for Colon Cancer: A Promising Model for Shared Decision Making
Blog
Colon Cancer Screening for Older Adults For adults ages 45 to 75, it is recommended to do routine screening for colorectal cancer — also called colon cancer — or for…
PCORI approves $123 million for research on postpartum care, hypertension management, antibiotic prescribing and a range of conditions
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $123 million to support 15 new research studies. These studies aim to fill evidence gaps, enhance…
PCORI approves $94 million to fund new colorectal cancer screening study in older adults and Phase 3 of PCORnet infrastructure project
News Release
WASHINGTON, DC—The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved an award slate with $32.7 million for a large, multi-phase comparative clinical effectiveness research (CER) study to compare…
PCORI-Funded Study Examining Treatment Options for Appendicitis Yields Useful Early Results
Blog
Early results from a PCORI-funded study show that seven in 10 adults with uncomplicated appendicitis were able to safely delay surgery for at least three months by taking a course…
Taking the Confusion out of Breast Cancer Screening
Blog
At its core, screening for breast cancer aims to save lives. The idea is intuitively attractive: Find a tumor early, before the disease becomes more serious, and some combination of…
The COMBINE TRIAL: Improving Treatment for Pediatric Crohn's Disease
Research Study Highlight
Pediatric patients receiving the tumor necrosis factor (TNF) inhibitor adalimumab, combined with a low dose of methotrexate, a second immunosuppressant, to treat Crohn’s disease did better than those treated with…
PRIMED Study: Training, Reminders Aid Talks about Colorectal Cancer Screening in Older Adults
Research Study Highlight
For older adults, guidelines recommend clinicians and patients work together to make decisions about colorectal cancer screening (CRC). However, these conversations must consider several factors and can be challenging. The…
TrACER Study: Changing Prescription Order Systems to Lower Risk of Febrile Neutropenia in Patients Starting Chemotherapy
Research Study Highlight
Some patients who receive chemotherapy develop a serious health problem called febrile neutropenia (FN), which involves having a fever and a low number of a type of white blood cells…
Emerging Health Care Innovation Brief: Treating Myotonic Dystrophy Type 1 and Expanded Use of Injectable Weight Loss Drugs
Highlight
The latest Emerging Health Care Innovation Brief looks at a few high-profile weight loss drugs that have received renewed attention with a recent policy decision that could expand their use…