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Colon Cancer Screening for Older Adults For adults ages 45 to 75, it is recommended to do routine screening for colorectal cancer — also called colon cancer — or for…

PCORI’s mandate is to improve the quality and relevance of evidence that can help patients, caregivers, clinicians and others make better-informed health or healthcare decisions. Our Evidence Updates are one…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $123 million to support 15 new research studies. These studies aim to fill evidence gaps, enhance…

The COVID-19 pandemic triggered many uncertainties and concerns for pregnant people, who were faced with navigating frequent prenatal and postpartum healthcare visits under risk of COVID-19 exposure. The pandemic has…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling $258 million to support 26 new research studies. These studies aim to fill evidence gaps and…

Conducting clinical research studies often takes years, from recruiting participants to analyzing data. It can often take many more years for new evidence from research to inform health care and…

WASHINGTON, DC—The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved an award slate with $32.7 million for a large, multi-phase comparative clinical effectiveness research (CER) study to compare…

Early results from a PCORI-funded study show that seven in 10 adults with uncomplicated appendicitis were able to safely delay surgery for at least three months by taking a course…

May is National Asthma Awareness Month—and a good time to highlight PCORI’s commitment to improving asthma care, with a particular focus on addressing racial and ethnic disparities in treatment outcomes…

Pediatric patients receiving the tumor necrosis factor (TNF) inhibitor adalimumab, combined with a low dose of methotrexate, a second immunosuppressant, to treat Crohn’s disease did better than those treated with…

An easy-to-use, patient-centered approach to managing moderate to severe asthma improved outcomes for African-American/Black and Hispanic/Latinx adults, according to findings of the PCORI-funded PREPARE study , published in The New…

For older adults, guidelines recommend clinicians and patients work together to make decisions about colorectal cancer screening (CRC). However, these conversations must consider several factors and can be challenging. The…

Some patients who receive chemotherapy develop a serious health problem called febrile neutropenia (FN), which involves having a fever and a low number of a type of white blood cells…