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Colon Cancer Screening for Older Adults For adults ages 45 to 75, it is recommended to do routine screening for colorectal cancer — also called colon cancer — or for…

Treatment-Resistant Depression Major depressive disorder is a serious health concern for adults in the United States. According to data from the Centers for Disease Control and Prevention, close to one…

What is peripartum depression? Peripartum depression is more than just “baby blues:” this condition is clinical depression experienced by a person during pregnancy or after giving birth that can continue…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today began inviting proposals for new studies and implementation projects through nine funding opportunities. These PCORI Funding Announcements (PFAs) include four…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $123 million to support 15 new research studies. These studies aim to fill evidence gaps, enhance…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has opened the application periods for nine funding opportunities that offer up to $308.5 million in total funding. The latest PCORI…

Editor's Note (February 27, 2023) These eight Topic Themes join four that are ongoing—preventing maternal morbidity and mortality, improving outcomes for people with intellectual or developmental disabilities, addressing COVID-19, and…

More than 100,000 people in the United States have sickle cell disease —a group of inherited red blood cell disorders that affect blood flow and the body’s use of oxygen…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling $258 million to support 26 new research studies. These studies aim to fill evidence gaps and…

Conducting clinical research studies often takes years, from recruiting participants to analyzing data. It can often take many more years for new evidence from research to inform health care and…

WASHINGTON, DC—The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved an award slate with $32.7 million for a large, multi-phase comparative clinical effectiveness research (CER) study to compare…

Telehealth—the use of digital information and communication technologies, such as computers and mobile devices, to access health care services remotely and manage health care—has grown in promise as technology has…

An estimated 43.6 million American adults—nearly one in five—have mental illness. Anxiety and mood disorders, including depression, are the most common forms. While these conditions are usually treatable, clinicians often…

Adults with anxiety disorders can experience comparable relief from either meditation or a commonly prescribed medication, according to findings from a PCORI-funded study published in JAMA Psychiatry . For the…

An estimated one in three people with clinical depression do not respond to antidepressants, limiting their treatment option to electroconvulsive therapy (ECT), which has been linked to physical and mental…

For older adults, guidelines recommend clinicians and patients work together to make decisions about colorectal cancer screening (CRC). However, these conversations must consider several factors and can be challenging. The…

September marks National Suicide Prevention Month, a time to raise awareness about suicide prevention and share messages of hope. Suicide is the leading cause of death among Alaska Native young…

Some patients who receive chemotherapy develop a serious health problem called febrile neutropenia (FN), which involves having a fever and a low number of a type of white blood cells…