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Patient-Centeredness for Treatment-Resistant Depression: Comparative Clinical Effectiveness Research Trial Tests a New Approach
Blog
Treatment-Resistant Depression Major depressive disorder is a serious health concern for adults in the United States. According to data from the Centers for Disease Control and Prevention, close to one…
Evidence Updates Share New Findings to Support Health Decision Making
Blog
PCORI’s mandate is to improve the quality and relevance of evidence that can help patients, caregivers, clinicians and others make better-informed health or healthcare decisions. Our Evidence Updates are one…
Reaching the Summit: Patient-Centered CER Helps Women Overcome Peripartum Depression
Blog
What is peripartum depression? Peripartum depression is more than just “baby blues:” this condition is clinical depression experienced by a person during pregnancy or after giving birth that can continue…
Placing Patient and Peer Voices at the Forefront: Engagement Projects Focus on Mental Health
Blog
Mental health conditions impact individuals across age, income, racial, and ethnic groups. One in five people in the United States will experience a mental health condition within a given year…
PCORI offers up to $452 million through new health research funding opportunities on various topics
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today began inviting proposals for new studies and implementation projects through nine funding opportunities. These PCORI Funding Announcements (PFAs) include four…
PCORI offers up to $308.5 million through new funding opportunities
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has opened the application periods for nine funding opportunities that offer up to $308.5 million in total funding. The latest PCORI…
PCORI approves $96 million for research on mental health, delirium, adolescent alcohol use among other conditions
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $96 million to support 18 new research studies. These studies aim to fill evidence gaps and…
Spotlight on National Sickle Cell Disease Awareness Month
Blog
More than 100,000 people in the United States have sickle cell disease —a group of inherited red blood cell disorders that affect blood flow and the body’s use of oxygen…
PCORI approves $258 million to fund research studies addressing mental health, heart-related care, and a range of chronic and acute conditions
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling $258 million to support 26 new research studies. These studies aim to fill evidence gaps and…
Evidence Updates Highlight New Findings from PCORI-Funded Research
Blog
Conducting clinical research studies often takes years, from recruiting participants to analyzing data. It can often take many more years for new evidence from research to inform health care and…
Helping Make Veterans Research More Patient-Centered
Blog
One of the goals PCORI set in its strategic plan is to influence research to become more patient-centered. Engaging patients and healthcare stakeholders in the research process is central to…
PCORI Researchers Are Answering Rapidly Emerging Questions about Telehealth
Blog
Telehealth—the use of digital information and communication technologies, such as computers and mobile devices, to access health care services remotely and manage health care—has grown in promise as technology has…
PCORI-Funded Projects Aim to Use Telehealth to Address Disparities
Blog
As Americans’ use of cell phones and the internet have increased rapidly, clinicians and researchers have realized that telehealth may help people better manage their health. Telehealth, which involves clinicians…
Research to Improve Minority Mental Health
Blog
One in six US adults lives with a mental illness such as depression, bipolar disorder, and anxiety disorders, according to the National Institute of Mental Health. Compared with non-Hispanic whites…
Drawing on Mental Health "Experts-by-Experience"
Blog
An estimated 43.6 million American adults—nearly one in five—have mental illness. Anxiety and mood disorders, including depression, are the most common forms. While these conditions are usually treatable, clinicians often…
New Research Funding Opportunities on Addressing Rare Diseases, Substance Use, and Other Topics Open May 7
Funding Announcement Notice
PCORI's Online System will open on May 7, 2024, for the submission of Letters of Intent (LOI) for several research PCORI Funding Announcements (PFA), which will fund proposals for high-quality…
Mindfulness-Based Stress Reduction Just as Safe, Effective as Common Medication for Anxiety Disorders, Study Finds
Research Study Highlight
Adults with anxiety disorders can experience comparable relief from either meditation or a commonly prescribed medication, according to findings from a PCORI-funded study published in JAMA Psychiatry . For the…
ELEKT-D Study: Ketamine as Effective as ECT for Treating Major Depression
Research Study Highlight
An estimated one in three people with clinical depression do not respond to antidepressants, limiting their treatment option to electroconvulsive therapy (ECT), which has been linked to physical and mental…
Virtual Applicant Town Halls for Upcoming Research Funding Opportunities: Register Now
Highlight
PCORI will be hosting several virtual applicant town halls for prospective applicants to learn more about the new Research PCORI Funding Announcements (PFAs) that open on May 7. Attendees will…
BeWeL Study: Award-Winning Video Seeks to Help Reduce Suicide Risk Among Alaska Native Young People
Research Study Highlight
September marks National Suicide Prevention Month, a time to raise awareness about suicide prevention and share messages of hope. Suicide is the leading cause of death among Alaska Native young…
Broad Pragmatic Studies: New Funding Opportunity for High-Impact, Long-Range Research Opens May 7
Funding Announcement Notice
On May 7, 2024, PCORI will begin accepting Letter of Intent (LOI) submissions for the Broad Pragmatic Studies PCORI Funding Announcement (BPS PFA) under Cycle 2 2024. This PFA seeks…
TrACER Study: Changing Prescription Order Systems to Lower Risk of Febrile Neutropenia in Patients Starting Chemotherapy
Research Study Highlight
Some patients who receive chemotherapy develop a serious health problem called febrile neutropenia (FN), which involves having a fever and a low number of a type of white blood cells…