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Patient-Centeredness for Treatment-Resistant Depression: Comparative Clinical Effectiveness Research Trial Tests a New Approach
Blog
Treatment-Resistant Depression Major depressive disorder is a serious health concern for adults in the United States. According to data from the Centers for Disease Control and Prevention, close to one…
Reaching the Summit: Patient-Centered CER Helps Women Overcome Peripartum Depression
Blog
What is peripartum depression? Peripartum depression is more than just “baby blues:” this condition is clinical depression experienced by a person during pregnancy or after giving birth that can continue…
Placing Patient and Peer Voices at the Forefront: Engagement Projects Focus on Mental Health
Blog
Mental health conditions impact individuals across age, income, racial, and ethnic groups. One in five people in the United States will experience a mental health condition within a given year…
PCORI offers up to $452 million through new health research funding opportunities on various topics
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today began inviting proposals for new studies and implementation projects through nine funding opportunities. These PCORI Funding Announcements (PFAs) include four…
PCORI offers up to $308.5 million through new funding opportunities
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has opened the application periods for nine funding opportunities that offer up to $308.5 million in total funding. The latest PCORI…
Spotlight on National Sickle Cell Disease Awareness Month
Blog
More than 100,000 people in the United States have sickle cell disease —a group of inherited red blood cell disorders that affect blood flow and the body’s use of oxygen…
PCORI approves $258 million to fund research studies addressing mental health, heart-related care, and a range of chronic and acute conditions
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling $258 million to support 26 new research studies. These studies aim to fill evidence gaps and…
Evidence Updates Highlight New Findings from PCORI-Funded Research
Blog
Conducting clinical research studies often takes years, from recruiting participants to analyzing data. It can often take many more years for new evidence from research to inform health care and…
PCORI Funding Opportunities Open September 7
Blog
Delivering on its commitment to develop an extensive pipeline of funding opportunities made earlier this year, PCORI opens its third funding cycle on September 7. The funding cycle includes nine…
Visualizing the Benefits and Harms of Drugs and Devices for Migraine Prevention
Blog
Migraine headache is a disabling condition that affects one in six Americans. Making sense of research results for the many treatments available for migraine is complicated. To help patients and…
More than a dozen research topics of interest approved for future PCORI funding opportunities
News Release
More than a dozen topics ranging from healthy aging to prevention of drug addiction among adolescents and from telehealth to addressing bias, racism and discrimination throughout the health care continuum will be the focus of efforts to develop future research funding opportunities from the Patient-Centered Outcomes Research Institute (PCORI) following approval at today’s PCORI Board of Governors meeting.
PCORI Researchers Are Answering Rapidly Emerging Questions about Telehealth
Blog
Telehealth—the use of digital information and communication technologies, such as computers and mobile devices, to access health care services remotely and manage health care—has grown in promise as technology has…
Research to Improve Minority Mental Health
Blog
One in six US adults lives with a mental illness such as depression, bipolar disorder, and anxiety disorders, according to the National Institute of Mental Health. Compared with non-Hispanic whites…
Drawing on Mental Health "Experts-by-Experience"
Blog
An estimated 43.6 million American adults—nearly one in five—have mental illness. Anxiety and mood disorders, including depression, are the most common forms. While these conditions are usually treatable, clinicians often…
Mindfulness-Based Stress Reduction Just as Safe, Effective as Common Medication for Anxiety Disorders, Study Finds
Research Study Highlight
Adults with anxiety disorders can experience comparable relief from either meditation or a commonly prescribed medication, according to findings from a PCORI-funded study published in JAMA Psychiatry . For the…
ELEKT-D Study: Ketamine as Effective as ECT for Treating Major Depression
Research Study Highlight
An estimated one in three people with clinical depression do not respond to antidepressants, limiting their treatment option to electroconvulsive therapy (ECT), which has been linked to physical and mental…
BeWeL Study: Award-Winning Video Seeks to Help Reduce Suicide Risk Among Alaska Native Young People
Research Study Highlight
September marks National Suicide Prevention Month, a time to raise awareness about suicide prevention and share messages of hope. Suicide is the leading cause of death among Alaska Native young…
MOTS Trial: Comparing Ways to Manage Symptoms for Patients Who Have Chronic Migraine and Frequent Medication Use
Research Study Highlight
Many people with chronic migraines use medication more often than recommended. This overuse can have the undesired effect of more migraines and headaches and other serious side effects. The PCORI-funded…
TrACER Study: Changing Prescription Order Systems to Lower Risk of Febrile Neutropenia in Patients Starting Chemotherapy
Research Study Highlight
Some patients who receive chemotherapy develop a serious health problem called febrile neutropenia (FN), which involves having a fever and a low number of a type of white blood cells…