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Treatment-Resistant Depression Major depressive disorder is a serious health concern for adults in the United States. According to data from the Centers for Disease Control and Prevention, close to one…

What is peripartum depression? Peripartum depression is more than just “baby blues:” this condition is clinical depression experienced by a person during pregnancy or after giving birth that can continue…

WASHINGTON, D.C. — The Patient-Centered Outcomes Research Institute (PCORI) today began inviting proposals for new studies and projects through 10 funding opportunities. Five of these PCORI Funding Announcements (PFAs) are…

WASHINGTON, D.C. — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $80.5 million to support four new, ambitious patient-centered comparative clinical effectiveness research (CER) studies focused on…

WASHINGTON, D.C. — The Patient-Centered Outcomes Research Institute (PCORI) today announced the approval of funding awards totaling $225 million, which include $207 million to support 20 new patient-centered comparative clinical…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $208 million to support 17 new comparative clinical effectiveness research (CER) studies, including four trials of…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $123 million to support 15 new research studies. These studies aim to fill evidence gaps, enhance…

With just about any health condition, early intervention offers the best chance for a positive outcome. The sooner a diagnosis is made, and treatment starts, the better chance a person…

About this Blog Series When Patrick Gee, PhD, first learned he needed dialysis, he was stunned. He had never even seen a kidney doctor before and was shocked to find…

More than 100,000 people in the United States have sickle cell disease —a group of inherited red blood cell disorders that affect blood flow and the body’s use of oxygen…

The COVID-19 pandemic triggered many uncertainties and concerns for pregnant people, who were faced with navigating frequent prenatal and postpartum healthcare visits under risk of COVID-19 exposure. The pandemic has…

WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling $258 million to support 26 new research studies. These studies aim to fill evidence gaps and…

Each week throughout April, in recognition of National Minority Health Month, PCORI will spotlight health conditions that disproportionately affect communities of color. One of PCORI's National Priorities for Health is…

Each week throughout April, in recognition of National Minority Health Month, PCORI will spotlight health conditions that disproportionately affect communities of color. One of PCORI's National Priorities for Health is…

Healthy kidneys are key to healthy bodies — acting as a filter so that the nutrients we need to stay in our bloodstream are kept circulating while waste products are…

Conducting clinical research studies often takes years, from recruiting participants to analyzing data. It can often take many more years for new evidence from research to inform health care and…

Every time a parent leaves our neonatal intensive care unit (NICU) to take their child home, we are asking them to do superhuman things. At Children’s National Hospital, the tasks…

Telehealth—the use of digital information and communication technologies, such as computers and mobile devices, to access health care services remotely and manage health care—has grown in promise as technology has…

An estimated 43.6 million American adults—nearly one in five—have mental illness. Anxiety and mood disorders, including depression, are the most common forms. While these conditions are usually treatable, clinicians often…

Adults with anxiety disorders can experience comparable relief from either meditation or a commonly prescribed medication, according to findings from a PCORI-funded study published in JAMA Psychiatry . For the…

About 37 million Americans live with chronic kidney disease (CKD) and may not know about their options for treatment or the benefits and harms of each choice. A PCORI-funded research…

An estimated one in three people with clinical depression do not respond to antidepressants, limiting their treatment option to electroconvulsive therapy (ECT), which has been linked to physical and mental…

September marks National Suicide Prevention Month, a time to raise awareness about suicide prevention and share messages of hope. Suicide is the leading cause of death among Alaska Native young…