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Patient-Centeredness for Treatment-Resistant Depression: Comparative Clinical Effectiveness Research Trial Tests a New Approach
Blog
Treatment-Resistant Depression Major depressive disorder is a serious health concern for adults in the United States. According to data from the Centers for Disease Control and Prevention, close to one…
Reaching the Summit: Patient-Centered CER Helps Women Overcome Peripartum Depression
Blog
What is peripartum depression? Peripartum depression is more than just “baby blues:” this condition is clinical depression experienced by a person during pregnancy or after giving birth that can continue…
PCORI to direct up to $600 million in health research funding spanning eight high-need areas impacting the nation's health
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved PCORI investing up to $600 million in patient-centered comparative clinical effectiveness research (CER) through the development…
PCORI offers up to $452 million through new health research funding opportunities on various topics
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) today began inviting proposals for new studies and implementation projects through nine funding opportunities. These PCORI Funding Announcements (PFAs) include four…
PCORI offers up to $308.5 million through new funding opportunities
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has opened the application periods for nine funding opportunities that offer up to $308.5 million in total funding. The latest PCORI…
Topic Themes: Informing Future PCORI Funding Opportunities
Blog
Editor's Note (February 27, 2023) These eight Topic Themes join four that are ongoing—preventing maternal morbidity and mortality, improving outcomes for people with intellectual or developmental disabilities, addressing COVID-19, and…
Spotlight on National Sickle Cell Disease Awareness Month
Blog
More than 100,000 people in the United States have sickle cell disease —a group of inherited red blood cell disorders that affect blood flow and the body’s use of oxygen…
PCORI approves $258 million to fund research studies addressing mental health, heart-related care, and a range of chronic and acute conditions
News Release
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling $258 million to support 26 new research studies. These studies aim to fill evidence gaps and…
Learning Drives Innovation in New PCORI Initiatives
Leadership Perspective
Our efforts to engage patients and stakeholders across the healthcare community, and focus on outcomes of interest to patients and those who care for them, are how we conduct Research…
MEDIA ADVISORY: PCORI Hosts Virtual Briefing on Suicide Prevention in Youth and Young Adults
News Release
WASHINGTON, DC—U.S. Reps. Ashley Hinson (R-Iowa) and Jamie Raskin (D-Md.) will kick off a virtual convening on suicide prevention with an emphasis on youth and young adults hosted by the…
Evidence Updates Highlight New Findings from PCORI-Funded Research
Blog
Conducting clinical research studies often takes years, from recruiting participants to analyzing data. It can often take many more years for new evidence from research to inform health care and…
Helping Make Veterans Research More Patient-Centered
Blog
One of the goals PCORI set in its strategic plan is to influence research to become more patient-centered. Engaging patients and healthcare stakeholders in the research process is central to…
PCORI-Funded Researchers Seek Ways to Address Youth Suicide
Blog
This month PCORI joins researchers, people with lived experience, health experts, medical professionals, and millions of other stakeholders to mark National Suicide Prevention Month. Suicide is the tenth leading cause…
PCORI approves $254 million to fund 28 new research studies addressing urgent health problems
News Release
The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved $254 million in funding for 28 new research studies aimed at eliminating disparities in maternal morbidity and mortality, preventing suicide among young people, and improving behavioral health, maternal and infant outcomes, cancer care, surgical care and outcomes for people with chronic illnesses such as cardiovascular disease and diabetes.
More than a dozen research topics of interest approved for future PCORI funding opportunities
News Release
More than a dozen topics ranging from healthy aging to prevention of drug addiction among adolescents and from telehealth to addressing bias, racism and discrimination throughout the health care continuum will be the focus of efforts to develop future research funding opportunities from the Patient-Centered Outcomes Research Institute (PCORI) following approval at today’s PCORI Board of Governors meeting.
PCORI Researchers Are Answering Rapidly Emerging Questions about Telehealth
Blog
Telehealth—the use of digital information and communication technologies, such as computers and mobile devices, to access health care services remotely and manage health care—has grown in promise as technology has…
New PFA Opens for Brief Interventions for Youth at Risk of Suicide
Blog
We opened our online system for an array of PCORI Funding Announcements (PFAs) September 1, including Suicide Prevention: Brief Interventions for Youth . This PFA was developed in response to…
Drawing on Mental Health "Experts-by-Experience"
Blog
An estimated 43.6 million American adults—nearly one in five—have mental illness. Anxiety and mood disorders, including depression, are the most common forms. While these conditions are usually treatable, clinicians often…
New Funding Opportunity on Substance Use/Misuse and Disorders Research Opens May 7
Funding Announcement Notice
On May 7, 2024, PCORI will begin accepting Letter of Intent (LOI) submissions for the Addressing Substance Use Topical PCORI Funding Announcement (PFA) under Cycle 2 2024. This Topical PFA…
New Research Funding Opportunities on Addressing Rare Diseases, Substance Use, and Other Topics Open May 7
Funding Announcement Notice
PCORI's Online System will open on May 7, 2024, for the submission of Letters of Intent (LOI) for several research PCORI Funding Announcements (PFA), which will fund proposals for high-quality…
Mindfulness-Based Stress Reduction Just as Safe, Effective as Common Medication for Anxiety Disorders, Study Finds
Research Study Highlight
Adults with anxiety disorders can experience comparable relief from either meditation or a commonly prescribed medication, according to findings from a PCORI-funded study published in JAMA Psychiatry . For the…
ELEKT-D Study: Ketamine as Effective as ECT for Treating Major Depression
Research Study Highlight
An estimated one in three people with clinical depression do not respond to antidepressants, limiting their treatment option to electroconvulsive therapy (ECT), which has been linked to physical and mental…
Virtual Applicant Town Halls for Upcoming Research Funding Opportunities: Register Now
Highlight
PCORI will be hosting several virtual applicant town halls for prospective applicants to learn more about the new Research PCORI Funding Announcements (PFAs) that open on May 7. Attendees will…
New Topical Funding Opportunities on Addressing Rare Diseases and Substance Use Open May 7
Funding Announcement Notice
On May 7, 2024, PCORI will begin accepting Letter of Intent (LOI) submissions for two topical PCORI funding announcements under Cycle 2 2024: Addressing Rare Diseases and Addressing Substance Use…
BeWeL Study: Award-Winning Video Seeks to Help Reduce Suicide Risk Among Alaska Native Young People
Research Study Highlight
September marks National Suicide Prevention Month, a time to raise awareness about suicide prevention and share messages of hope. Suicide is the leading cause of death among Alaska Native young…