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COVID Watch Study: Pulse Oximeters Shown Not to Improve Outcomes for Patients with COVID-19 Recovering at Home
Study Highlight
Patients with COVID-19 who were remotely monitored at home using a text-message-based program — known as COVID Watch — did not experience better outcomes if they used a pulse oximeter…
'Hearing Norton Sound' Study: Telehealth Referrals Improve Access to Hearing Care for Children in Rural Areas
Study Highlight
Children in school-based hearing screening programs who received telehealth-based specialist referrals experienced follow-up care up to 17.6 times faster, compared with children who received standard primary care referrals, according to…
PREVENT CLOT Study: Aspirin as Effective as Injectable Blood Thinner to Prevent Blood Clots
Study Highlight
Over-the-counter aspirin is as effective as low-molecular-weight heparin, a commonly used injectable blood thinner, in preventing life-threatening blood clots among patients hospitalized due to a fracture, according to findings from…
Can Patients with MS Safely Stop Taking Medicine as They Age? DISCOMS Trial's Results Indicate It's a Reasonable Option for Some
Study Highlight
Although new results from an ongoing PCORI-funded study into whether some patients with multiple sclerosis (MS) can safely stop taking certain kinds of medications as they age weren’t conclusive in…
Study: COVID-19 Healthcare Workers Experienced Rates of Moral Injury Similar to Combat Veterans
Study Highlight
A PCORI-funded research registry of more than 55,000 healthcare workers and their families has powered a study that provides important insights into the psyche of COVID-19 healthcare workers during the…
PRIMED Study: Training, Reminders Aid Talks about Colorectal Cancer Screening in Older Adults
Study Highlight
For older adults, guidelines recommend clinicians and patients work together to make decisions about colorectal cancer screening (CRC). However, these conversations must consider several factors and can be challenging. The…
The KIDCARE Study: Exploring Treatment Strategies for Rare Pediatric Illness
Study Highlight
Kawasaki disease is a rare form of cardiovascular disease that mainly affects children. The condition causes widespread inflammation and can lead to focal swelling, or aneurysm formation, of the arteries…
REGAIN Trial: Comparing How Two Types of Anesthesia Affect Recovery from Hip Fracture Surgery
Study Highlight
Each year, more than 300,000 adults in the United States break a hip and nearly all will need surgery. The PCORI-funded REGAIN Trial, comparing how general anesthesia and spinal anesthesia…
The COMBINE TRIAL: Improving Treatment for Pediatric Crohn's Disease
Study Highlight
Pediatric patients receiving the tumor necrosis factor (TNF) inhibitor adalimumab, combined with a low dose of methotrexate, a second immunosuppressant, to treat Crohn’s disease did better than those treated with…
Study: Heart Complication Risk Higher After COVID-19 Infection Than Vaccination
Study Highlight
Results of a study appearing in the April 1 issue of the CDC's Morbidity and Mortality Weekly Report will enable a better understanding about the comparative risks of heart complications…
BP-CHECK Study: Comparing Home, Clinic, and Kiosk Blood Pressure Monitoring
Study Highlight
Proper diagnosis of hypertension can save a patient’s life. But blood pressure varies a lot over the day and one or two measurements in a clinic may not reflect a…
PCORnet® Powers Study Providing New Evidence About 'Long COVID'
Study Highlight
A new, large study involving more than 2 million anonymized patient records found roughly one in 10 people infected with COVID-19 developed new symptoms or health conditions associated with what’s…
PRO-TECT Trial: Telehealth Interventions Improve Outcomes for Patients with Advanced Cancer
Study Highlight
Patients with advanced cancer who used telehealth to regularly report symptoms improved their overall well-being, compared with those who were seen less frequently via in-person clinical visits, according to results…
MOTS Trial: Comparing Ways to Manage Symptoms for Patients Who Have Chronic Migraine and Frequent Medication Use
Study Highlight
Many people with chronic migraines use medication more often than recommended. This overuse can have the undesired effect of more migraines and headaches and other serious side effects. The PCORI-funded…
TrACER Study: Changing Prescription Order Systems to Lower Risk of Febrile Neutropenia in Patients Starting Chemotherapy
Study Highlight
Some patients who receive chemotherapy develop a serious health problem called febrile neutropenia (FN), which involves having a fever and a low number of a type of white blood cells…
COVID Watch Study: Automated Texting System Saved COVID-19 Patients’ Lives
Study Highlight
A system designed to monitor COVID-19 patients at home using automated text messages saved a life about twice a week during the early days of the pandemic, and overall, patients…
PREPARE Study: Reducing the Impact of Asthma on Underserved Populations
Study Highlight
An easy-to-use, patient-centered approach to managing moderate to severe asthma improved outcomes for African-American/Black and Hispanic/Latinx adults, according to findings of the PCORI-funded PREPARE study, published in The New England…
Study Using PCORnet® Suggests Disparities in Receipt of COVID-19 Medications
Study Highlight
Underscoring the health inequities that have characterized the COVID-19 pandemic, an analysis of health data accessed via a PCORI-funded network suggests that monoclonal antibodies, medications highly effective at lessening the…
Mindfulness-Based Stress Reduction Just as Safe, Effective as Common Medication for Anxiety Disorders, Study Finds
Study Highlight
Adults with anxiety disorders can experience comparable relief from either meditation or a commonly prescribed medication, according to findings from a PCORI-funded study published in JAMA Psychiatry. For the study…
Online Decision Aid Helping Patients with Kidney Disease Make Treatment Decisions, PCORI-Funded DART Study Finds
Study Highlight
About 37 million Americans live with chronic kidney disease (CKD) and may not know about their options for treatment or the benefits and harms of each choice. A PCORI-funded research…