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PCORnet® Powers Study Providing New Evidence About 'Long COVID'
Research Study Highlight
A new, large study involving more than 2 million anonymized patient records found roughly one in 10 people infected with COVID-19 developed new symptoms or health conditions associated with what’s…
BP-CHECK Study: Comparing Home, Clinic, and Kiosk Blood Pressure Monitoring
Research Study Highlight
Proper diagnosis of hypertension can save a patient’s life. But blood pressure varies a lot over the day and one or two measurements in a clinic may not reflect a…
Study: Heart Complication Risk Higher After COVID-19 Infection Than Vaccination
Research Study Highlight
Results of a study appearing in the April 1 issue of the CDC's Morbidity and Mortality Weekly Report will enable a better understanding about the comparative risks of heart complications…
REGAIN Trial: Comparing How Two Types of Anesthesia Affect Recovery from Hip Fracture Surgery
Research Study Highlight
Each year, more than 300,000 adults in the United States break a hip and nearly all will need surgery. The PCORI-funded REGAIN Trial , comparing how general anesthesia and spinal…
The COMBINE TRIAL: Improving Treatment for Pediatric Crohn's Disease
Research Study Highlight
Pediatric patients receiving the tumor necrosis factor (TNF) inhibitor adalimumab, combined with a low dose of methotrexate, a second immunosuppressant, to treat Crohn’s disease did better than those treated with…
CANVAS Trial: Oral Blood Thinner as Effective as Injectable Type in Preventing Blood Clots in Adults with Cancer
Research Study Highlight
Adults with cancer who took a newer oral blood thinner to prevent recurrent venous thromboembolism (VTE), or blood clots, fared just as well as those who took an older injectable…
Study Using PCORnet® Suggests Disparities in Receipt of COVID-19 Medications
Research Study Highlight
Underscoring the health inequities that have characterized the COVID-19 pandemic, an analysis of health data accessed via a PCORI-funded network suggests that monoclonal antibodies, medications highly effective at lessening the…
PREPARE Study: Reducing the Impact of Asthma on Underserved Populations
Research Study Highlight
An easy-to-use, patient-centered approach to managing moderate to severe asthma improved outcomes for African-American/Black and Hispanic/Latinx adults, according to findings of the PCORI-funded PREPARE study , published in The New…
Mindfulness-Based Stress Reduction Just as Safe, Effective as Common Medication for Anxiety Disorders, Study Finds
Research Study Highlight
Adults with anxiety disorders can experience comparable relief from either meditation or a commonly prescribed medication, according to findings from a PCORI-funded study published in JAMA Psychiatry . For the…
Online Decision Aid Helping Patients with Kidney Disease Make Treatment Decisions, PCORI-Funded DART Study Finds
Research Study Highlight
About 37 million Americans live with chronic kidney disease (CKD) and may not know about their options for treatment or the benefits and harms of each choice. A PCORI-funded research…
ELEKT-D Study: Ketamine as Effective as ECT for Treating Major Depression
Research Study Highlight
An estimated one in three people with clinical depression do not respond to antidepressants, limiting their treatment option to electroconvulsive therapy (ECT), which has been linked to physical and mental…
Study: COVID-19 Healthcare Workers Experienced Rates of Moral Injury Similar to Combat Veterans
Research Study Highlight
A PCORI-funded research registry of more than 55,000 healthcare workers and their families has powered a study that provides important insights into the psyche of COVID-19 healthcare workers during the…
Can Patients with MS Safely Stop Taking Medicine as They Age? DISCOMS Trial's Results Indicate It's a Reasonable Option for Some
Research Study Highlight
Although new results from an ongoing PCORI-funded study into whether some patients with multiple sclerosis (MS) can safely stop taking certain kinds of medications as they age weren’t conclusive in…
PRIMED Study: Training, Reminders Aid Talks about Colorectal Cancer Screening in Older Adults
Research Study Highlight
For older adults, guidelines recommend clinicians and patients work together to make decisions about colorectal cancer screening (CRC). However, these conversations must consider several factors and can be challenging. The…
The KIDCARE Study: Exploring Treatment Strategies for Rare Pediatric Illness
Research Study Highlight
Kawasaki disease is a rare form of cardiovascular disease that mainly affects children. The condition causes widespread inflammation and can lead to focal swelling, or aneurysm formation, of the arteries…
BeWeL Study: Award-Winning Video Seeks to Help Reduce Suicide Risk Among Alaska Native Young People
Research Study Highlight
September marks National Suicide Prevention Month, a time to raise awareness about suicide prevention and share messages of hope. Suicide is the leading cause of death among Alaska Native young…
MOTS Trial: Comparing Ways to Manage Symptoms for Patients Who Have Chronic Migraine and Frequent Medication Use
Research Study Highlight
Many people with chronic migraines use medication more often than recommended. This overuse can have the undesired effect of more migraines and headaches and other serious side effects. The PCORI-funded…
COVID Watch Study: Automated Texting System Saved COVID-19 Patients’ Lives
Research Study Highlight
A system designed to monitor COVID-19 patients at home using automated text messages saved a life about twice a week during the early days of the pandemic, and overall, patients…
PRO-TECT Trial: Telehealth Interventions Improve Outcomes for Patients with Advanced Cancer
Research Study Highlight
Patients with advanced cancer who used telehealth to regularly report symptoms improved their overall well-being, compared with those who were seen less frequently via in-person clinical visits, according to results…
TrACER Study: Changing Prescription Order Systems to Lower Risk of Febrile Neutropenia in Patients Starting Chemotherapy
Research Study Highlight
Some patients who receive chemotherapy develop a serious health problem called febrile neutropenia (FN), which involves having a fever and a low number of a type of white blood cells…
COVID Watch Study: Pulse Oximeters Shown Not to Improve Outcomes for Patients with COVID-19 Recovering at Home
Research Study Highlight
Patients with COVID-19 who were remotely monitored at home using a text-message-based program — known as COVID Watch — did not experience better outcomes if they used a pulse oximeter…
'Hearing Norton Sound' Study: Telehealth Referrals Improve Access to Hearing Care for Children in Rural Areas
Research Study Highlight
Children in school-based hearing screening programs who received telehealth-based specialist referrals experienced follow-up care up to 17.6 times faster, compared with children who received standard primary care referrals, according to…
PREVENT CLOT Study: Aspirin as Effective as Injectable Blood Thinner to Prevent Blood Clots
Research Study Highlight
Over-the-counter aspirin is as effective as low-molecular-weight heparin, a commonly used injectable blood thinner, in preventing life-threatening blood clots among patients hospitalized due to a fracture, according to findings from…