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PCORI’s mandate is to improve the quality and relevance of evidence that can help patients, caregivers, clinicians and others make better-informed health or healthcare decisions. Our Evidence Updates are one…

About this Blog Series Kristin Lee Berg, PhD, LCSW, was never a rebellious teenager, but she did have to navigate total vision loss in one eye and partial blindness in…

Editor's Note (February 27, 2023) These eight Topic Themes join four that are ongoing—preventing maternal morbidity and mortality, improving outcomes for people with intellectual or developmental disabilities, addressing COVID-19, and…

Conducting clinical research studies often takes years, from recruiting participants to analyzing data. It can often take many more years for new evidence from research to inform health care and…

This month PCORI joins researchers, people with lived experience, health experts, medical professionals, and millions of other stakeholders to mark National Suicide Prevention Month. Suicide is the tenth leading cause…

ABC News’ flagship morning program Good Morning America recently featured an online story on care for people with Down syndrome that highlighted a PCORI-funded project. The story about 28-year-old Cristina…

We opened our online system for an array of PCORI Funding Announcements (PFAs) September 1, including Suicide Prevention: Brief Interventions for Youth . This PFA was developed in response to…

Mental health is a topic that some people feel uncomfortable discussing. But failing to spread mental health awareness can have serious consequences. For example, people with serious mental illness (SMI)—conditions…

As Americans’ use of cell phones and the internet have increased rapidly, clinicians and researchers have realized that telehealth may help people better manage their health. Telehealth, which involves clinicians…

Nearly one-fifth of American children have obesity, increasing their risk of many associated health problems. These include conditions historically considered adult problems: heart disease, type 2 diabetes, high cholesterol, high…

Despite the name, "rare diseases" affect 30 million Americans. And their impact is severe—some of these illnesses have no effective treatment, and many are debilitating and life threatening. Yet each…