Program Overview

Under the auspices of our Research Infrastructure program, PCORI has funded the development of a national resource called PCORnet®, the National Patient-Centered Clinical Research Network. PCORnet is designed to improve the nation’s capacity to conduct patient-centered health research, particularly comparative effectiveness research (CER), efficiently, and to learn from the healthcare experiences of millions of Americans to allow for large-scale research to be conducted with enhanced accuracy and efficiency.

PCORnet is a “network of networks” that harnesses the power of large amounts of health information, including data from electronic health records, while leveraging strong partnerships between patients, clinicians, health plans, and health systems. PCORnet consists of eight Clinical Research Networks (CRNs) supported by PCORI. CRNs consist of two or more healthcare systems, including hospitals, integrated delivery systems, and federally qualified health centers. There are more than forty health systems participating in PCORnet through the CRNs. The CRNs transform data gathered from routine patient care across their participating health systems to a consistent format, the PCORnet Common Data Model (CDM), to enable rapid response to research-related questions. The Coordinating Center for PCORnet maintains the PCORnet CDM and serves as a central hub for the Network, bringing the diverse PCORnet networks, institutions, and patients together through shared communications, meetings, and initiatives.

This broad infrastructure can support researchers conducting large observational studies that include clinical and patient-reported outcomes as well as large, pragmatic clinical trials embedded within participating systems. To learn more about PCORnet, click here.

Image

TBA

PCORI has invested more than $460 million in infrastructure funding for PCORnet in a phased approach. Previous phases of PCORI funding have supported infrastructure planning (phase 1) and infrastructure implementation and capacity building (phase 2). For the current phase (phase 3), the PCORI Board of Governors developed and approved the Prioritizing Principles for Infrastructure Funding Relating to PCORnet to guide decision making about PCORI infrastructure funding for the optimization of PCORnet. Aligned with these principles, in Phase 3 of PCORnet, this “network of networks” is intended to optimize its capacity to serve as a national resource for conducting rapid, efficient, patient-centered CER that improves healthcare delivery and health outcomes. In alignment with the Prioritizing Principles for Infrastructure Funding Relating to PCORnet, PCORI engaged in a multi-stakeholder effort to identify opportunities for social determinants of health data infrastructure enhancements to PCORnet.

To read the Expanding Social Determinants of Health (SDOH) Data across PCORnet Clinical Research Networks White Paper, click here.

Impact

PCORnet Network Partners use visual metric tracking or a “dashboard” for evaluating progress in serving as a national resource to support multi-network, patient-centered observational and interventional research.

View the PCORnet Dashboard


Posted: February 25, 2016; Updated: May 11, 2022

What's Happening at PCORI?

The Patient-Centered Outcomes Research Institute sends weekly emails about opportunities to apply for funding, newly funded research studies and engagement projects, results of our funded research, webinars, and other new information posted on our site.

Subscribe to PCORI Emails

Image

Hand pointing to email icon