The Patient-Centered Outcomes Research Institute occupies a unique place in health care and health research. PCORI funds patient-centered comparative clinical effectiveness research to assist patients, clinicians, purchasers, policymakers, and the broader healthcare community in making informed health decisions. Guidance from a wide range of health stakeholders ensures that the research and initiatives PCORI funds are relevant and that our stakeholders are engaged throughout the research lifecycle, from developing research topics to ensuring the use and uptake of study findings.

PCORI's congressional authorization requires identification of National Priorities and establishment of a Research Agenda outlining how PCORI will address each priority. These documents guide our work. Hundreds of stakeholder representatives, advisors, and experts are informing our process, strategic approach, and various content elements, such as the proposed priorities.

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National Priorities for Health

In June 2021, the PCORI Board of Governors voted to release for public comment five proposed National Priorities for Health. PCORI will work toward these broad, ambitious goals through our Research Agenda, stakeholder engagement, dissemination and implementation efforts, and health communication. These National Priorities for Health represent an ambitious new approach to direct our work in the years ahead.

After a 60-day public comment period in the summer of 2021 and various meetings and regional convenings on research and health, PCORI refined the proposed National Priorities for Health to reflect the substantial input received from a wide range of stakeholders. On October 26, 2021, PCORI’s Board of Governors adopted the National Priorities for Health, which will serve as the foundation for developing PCORI’s Research Agenda, which we intend to present for public comment in December 2021.

National Priorities for Health: A Closer Look

Here are the adopted National Priorities for Health and the goal each seeks to achieve:

  • Increase Evidence for Existing Interventions and Emerging Innovations in Health

    • Goal: Strengthen and expand ongoing comparative clinical effectiveness research focused on both existing interventions and emerging innovations to improve healthcare practice, health outcomes, and health equity.
  • Enhance Infrastructure to Accelerate Patient-Centered Outcomes Research

    • Goal: Enhance the infrastructure that facilitates patient-centered outcomes research to drive lasting improvements in health and transformation of both the research enterprise and care delivery.
  • Advance the Science of Dissemination, Implementation, and Health Communication

    • Goal: Advance the scientific evidence for and the practice of dissemination, implementation, and health communication to accelerate the effective sharing of comparative clinical effectiveness research results for public understanding and uptake into practice.
  • Achieve Health Equity

    • Goal: Expand stakeholder engagement, research, and dissemination approaches that lead to continued progress toward achieving health equity in the United States.
  • Accelerate Progress Toward an Integrated Learning Health System

    • Goal: Foster actionable, timely, place-based, and transformative improvements in patient-centered experiences, care provision, and ultimately improved health outcomes through collaborative, multisectoral research to support a health system that understands and serves the needs and preferences of individuals.

Read More About the Proposed Priorities

Related Events

Virtual Community Convenings on Research and Health

PCORI hosted a series of virtual meetings in Colorado, Maryland and West Virginia to hear from a diverse range of individuals about key themes relevant to the proposed National Priorities. These meetings were open to the public and registration was required.

Proposed National Priorities for Health: Public Comment
(June 28 - August 27, 2021)

PCORI held a 60-day comment period, during which we invited comments from the public and stakeholder communities in English and in Spanish.

View the Submitted Comments

Kickoff Webinar for Proposed Priorities (June 29, 2021)

During this special webinar, PCORI staff described the proposed priorities, outlined PCORI's mission, and highlighted ways to provide input on the proposed priorities and other elements of our strategic planning process. The webinar also shared ways to become involved with PCORI's work.

Watch Recording


Posted: June 22, 2021; Updated: October 26, 2021

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