Opening conversations on patient-centered CER with PCORI 

Each year as part of the PCORI Annual Meeting, patients, caregivers, researchers and the broader healthcare community gather to discuss the latest in patient-centered clinical comparative effectiveness research (CER). While the event always affords rich dialogue and strengthened connections, at the 2023 Annual Meeting, one session in particular allowed participants to ask... anything of the PCORI program staff and PCORI-funded researchers. 

For first-time applicants in particular, Town Halls are an excellent opportunity to get an overview of PCORI as an organization as well as the specific nuances and expectations of the funding announcement of interest.

Your questions, answered 

Questions about PCORI funding were most common including, how much stakeholder engagement is expected (answer: a great deal), what makes PCORI different from other funders (see previous answer regarding high levels of engagement), and where to begin as a first-time applicant.  

For first-time applicants, PCORI Town Halls stood out as excellent opportunities to get an overview of PCORI as an organization as well as the specific nuances and expectations of the funding announcement of interest. Even for those who do not have a specific question in mind, it can be helpful to hear the types of questions that others ask. Each Town Hall is recorded and posted to PCORI’s website for later viewing.  

Additionally, some common, core tenets to keep in mind include:   

  • Applying for funding from PCORI is a two-stage process. A Letter of Intent (LOI) must be submitted first, and an organization must then be invited to submit a full application. 
  • An LOI must include a clear CER research question addressing an evidence gap and detailed information regarding the proposed comparators with evidence of efficacy or widespread use. 

Reach out to learn more 

For anyone who is considering applying for PCORI funding, the key piece of advice PCORI staff would give is: “Reach out to us!”  

In every stage of the process, there is ample opportunity contact PCORI program staff, including from pre-LOI submission to after LOI feedback is sent. Prospective applicants should also take advantage of the wealth of information on the PCORI website, while keeping in mind that PCORI staff are here to help. 

Even beyond their helpfully themed Annual Meeting session, then, the message from PCORI staff is clear: Ask Them Anything!

All sessions of the 2023 PCORI Annual Meeting are available to stream anytime, anywhere and for free at View the recordings today for a wealth of information on applying for PCORI funding and much, much more.

What's Happening at PCORI?

The Patient-Centered Outcomes Research Institute sends weekly emails about opportunities to apply for funding, newly funded research studies and engagement projects, results of our funded research, webinars, and other new information posted on our site.

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