- The PCORI Strategic Plan
- Our Programs
- Our Vision & Mission
- Financial Statements and Reports
- The PCORI Strategic Plan
- Board of Governors
- Methodology Committee
- Authorizing Law
- Evaluating Our Work
- PCORI's Advisory Panels
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Past Opportunities to Provide Input
- Systematic Review of Audio Care for the Management of Mental Health and Chronic Conditions (2023) -- Draft Key Questions
- Proposed New Methodology Standards for Usual Care as a Comparator (2023)
- Stakeholder Views on Components of 'Patient-Centered Value' in Health and Health Care (2023)
- PCORI's Proposed Research Agenda (2021-2022)
- Proposed National Priorities for Health (2021)
- Proposed Principles for the Consideration of the Full Range of Outcomes Data in PCORI-Funded Research (2020)
- Proposed New PCORI Methodology Standards (2018)
- Data Access and Data Sharing Policy: Public Comment (2017)
- Proposed New PCORI Methodology Standards (2017)
Comment on the Proposed New and Revised PCORI Methodology Standards (2016)
- 1. Standards for Formulating Research Questions
- 10: Standards for Studies of Diagnostic Tests
- 12. Standards on Research Designs Using Clusters
- 13: General Comments on the Proposed Revisions to the PCORI Methodology Standards
- 2: Standards Associated with Patient-Centeredness
- 3: Standards for Data Integrity and Rigorous Analysis
- 4: Standards for Preventing and Handling Missing Data
- 5: Standards for Heterogeneity of Treatment Effects
- 6: Standards for Data Registries
- 7: Standards for Data Networks as Research-Facilitating Structures
- 8. Standards for Causal Inference Methods
- 9. Standards for Adaptive Trial Designs
- Peer-Review Process Comments (2014)
- Draft Methodology Report Public Comment Period (2012)
Building on our hallmark of engaging healthcare stakeholders in all phases of research, PCORI is excited to join the American Heart Association (AHA) in announcing a crowdsourcing challenge for clinicians and researchers across the country. We’re looking for the best ideas for new research questions that address difficult challenges identified by patients with cardiovascular diseases.
Proposed hypotheses should focus on questions that can be answered by comparative clinical effectiveness research (CER), which compares the benefits and risks of alternate healthcare methods. Submissions should use a precision medicine approach, which takes into account individual patients’ genetics, environmental factors, lifestyle, and other characteristics.
We’ll select four research hypotheses and give each of the winning submitters a $5,000 prize. And we’ll consider these research questions for future funding opportunities.
With this clinician/researcher challenge, we are continuing to test-drive a crowdsourcing model for engaging the healthcare community in identifying important research topics.
PCORI's Cardiovascular Disease Focus
PCORI has funded 48 patient-centered comparative clinical effectiveness studies, totaling $178 million, related to heart disease, stroke, and other cardiovascular diseases (CVDs).
These projects, representing about 9 percent of the research portfolio, include assessments of heart disease interventions, projects testing the effectiveness of decision-support tools, and research that addresses information and communication gaps that may lead to poor patient outcomes.
For more information, see our fact sheet and a list of CVD projects.
Taking Advantage of Patient Input
This contest follows up on a previous AHA/PCORI challenge issued to patients and caregivers to identify important dilemmas they have faced in seeking treatment for cardiovascular diseases. Entrants in the new contest must address one or more of the patient or caregiver groups identified by the previous challenge:
- Patients with congestive heart failure
- Nonelderly patients with coronary heart disease
- Patients who experience a stroke
- Patients with lupus, rheumatoid arthritis, or other autoimmune conditions, who experience a stroke
- Elderly patients with aortic stenosis—a narrowing of the heart’s aortic valve that restricts blood flow
- Parents or caregivers of newborns with congenital heart disease
- Patients with atrial arrhythmia—an irregular heartbeat that can lead to blood clots, stroke, heart failure, or other complications
Coming Up with Winning Hypotheses
What are we looking for in submitted research questions? Among the questions that can be answered by CER with a precision medicine approach, we prefer hypotheses with strong potential for research that improves care options for people with heart-health problems.
The deadline for entries, which must be submitted here, is Thursday, October 6, 2016.
Given the burdens that cardiovascular diseases impose on our nation—the AHA estimates that these conditions cost the nation $316 billion annually in healthcare expenses and lost productivity— there’s great need and opportunity to improve care. With the input from patients, caregivers, clinicians, and researchers, our organizations can make a lasting impact through research that improves treatment for heart disease and stroke.
September 21, 2016, 12:48 PM
Comment by PCORI,
Hi Nausheen. Thank you for your comment and interest in this Challenge. Please submit your entry through crowdsourcing challenge link in the blog and to learn more about the challenge.
September 20, 2016, 10:32 PM
Comment by Nausheen Habib,
For individuals who have experienced congestive heart failure, is there a clinical benefit to utilizing both traditional treatments and complementary and alternative medicine (CAM) techniques as opposed to solely traditional (western) treatment?
September 9, 2016, 3:35 PM
Comment by PCORI,
Sam, thank you for your interest in this Challenge. Please use the crowdsourcing challenge link in the blog to learn more about the challenge.
September 7, 2016, 6:01 PM
Comment by Sam Lim,
What is the impact of social determinants of health on cardiovascular disease and its implications in better understanding health disparities?
What's Happening at PCORI?
The Patient-Centered Outcomes Research Institute sends weekly emails about opportunities to apply for funding, newly funded research studies and engagement projects, results of our funded research, webinars, and other new information posted on our site.