Skip to main content
Patient-Centered Outcomes Research Institute
Patient-Centered Outcomes Research Institute
  • Blog
  • Newsroom
  • Find It Fast
  • Help Center
  • Subscribe
  • Careers
  • Contact Us

PCORI

Patient-Centered Outcomes Research Institute

Search form

  • About Us
    Close mega-menu

    About Us

    • Our Programs
    • Governance
    • Financials and Reports
    • Procurement Opportunities
    • Our Staff
    • Our Vision & Mission
    • Contact Us

    Fact Sheets: Learn More About PCORI

    Download fact sheets about out work, the research we fund, and our programs and initiatives.

    Find It Fast

    Browse through an alphabetical list of frequently accessed and searched terms for information and resources.

    Subscribe to PCORI Email Alerts

    Sign up for weekly emails to stay current on the latest results of our funded projects, and more.

  • Research & Results
    Close mega-menu

    Research & Results

    • Explore Our Portfolio
    • Research Fundamentals
    • Research Results Highlights
    • Putting Evidence to Work
    • Peer Review
    • Evidence Synthesis
    • About Our Research

    Evidence Updates from PCORI-Funded Studies

    These updates capture highlights of findings from systematic reviews and our funded research studies.

    Journal Articles About Our Funded Research

    Browse through a collection of journal publications that provides insights into PCORI-funded work.

    Explore Our Portfolio of Funded Projects

    Find out about projects based on the health conditions they focus on, the state they are in, and if they have results.

  • Topics
    Close mega-menu

    Topics

    • Addressing Disparities
    • Arthritis
    • Asthma
    • Cancer
    • Cardiovascular Disease
    • Children's Health
    • Community Health Workers
    • COVID-19
    • Dementia and Cognitive Impairment
    • Diabetes
    • Intellectual and/or Developmental Disabilities
    • Kidney Disease
    • Maternal Morbidity and Mortality
    • Medicaid
    • Men's Health
    • Mental and Behavioral Health
    • Minority Mental Health
    • Multiple Chronic Conditions
    • Multiple Sclerosis
    • Obesity
    • Older Adults' Health
    • Pain Care and Opioids
    • Rare Diseases
    • Rural Health
    • Shared Decision Making
    • Telehealth
    • Transitional Care
    • Veterans Health
    • Women's Health

    Featured Topic: Women's Health

    Learn more about the projects we support on conditions that specifically or more often affect women.

  • Engagement
    Close mega-menu

    Engagement

    • The Value of Engagement
    • Engagement in Health Research Literature Explorer
    • Influencing the Culture of Research
    • Engagement Awards
    • Engagement Resources
    • Engage with Us

    Engagement Tools and Resources for Research

    This searchable peer-to-peer repository includes resources that can inform future work in patient-centered outcomes research.

    Engagement Awards

    Learn about our Engagement Awards program and view the announcements of all our open funding opportunities.

    Research Fundamentals: A New On-Demand Training

    It enables those new to health research or patient-centered research to learn more about the research process.

  • Funding Opportunities
    Close mega-menu

    Funding Opportunities

    • What & Who We Fund
    • What You Need to Know to Apply
    • Applicant Training
    • Merit Review
    • Awardee Resources
    • Help Center

    PCORI Funding Opportunities

    View and learn about the newly opened funding announcements and the upcoming PFAs in 2021.

    Tips for Submitting a Responsive LOI

    Find out what PCORI looks for in a letter of intent (LOI) along with other helpful tips.

    PCORI Awardee Resources

    These resources can help awardees in complying with the terms and conditions of their contract.

  • Meetings & Events
    Close mega-menu

    Meetings & Events

    • Upcoming
    • Past Events

    PCORI 2021 and Beyond

    During this webinar, PCORI leaders shared ways to get involved in PCOR, improvements to our funding opportunities, and more.

    2020 PCORI Annual Meeting

    Watch recordings of sessions and view titles and descriptions of posters presented at the virtual meeting.

    PCORI Board of Governors Meeting: April 13, 1:00pm ET

    Tune in as the Board discusses possible topics in the development of upcoming PCORI Funding Announcements, among other business. Register now.

You are here

  • Blog
  • COVID-19, Other Research Funding Oppo...

COVID-19, Other Research Funding Opportunities Open for Proposals

Date: 
May 5, 2020
Blog Topics: 
Funding Awards,
Research

As COVID-19 continues to present unique healthcare challenges to our nation, PCORI in turn continues to consider how we can best contribute to ongoing efforts to combat it hand in hand with government, industry, and other funders.

As you read in April, PCORI launched the HERO Registry and study to answer questions about the impact of COVID-19 on healthcare workers' lives. We also posted a funding opportunity to explore adding COVID-19-related aims to existing research projects, launched an Engagement Awards special cycle, and have held a series of webinars highlighting the demands the virus is placing on our hospitals and healthcare systems.

And now we are issuing a new COVID-19 funding announcement of up to $30 million with an accelerated timeline to support innovative, high-impact studies that fit clearly within our core mission of patient-engaged and patient-centered comparative clinical effectiveness research. The announcement seeks to strengthen the understanding of different approaches to mitigate the impact of COVID-19 on individuals, communities, healthcare providers, and healthcare systems, and to provide evidence to inform clinical and public health responses, decision making, and planning. Because of the critical need that the pandemic presents, we encourage applicants to provide actionable findings in no longer than 12 months.

Moving Quickly to Respond to the Health Emergency

Recognizing the critical urgency of the current pandemic, PCORI is waiving its usual Letter of Intent process for proposals. Full applications are due on May 26—three weeks from today—so that these urgent projects can get off the ground quickly. This funding announcement has three targeted priority areas.

  • Adaptations to healthcare delivery. What has been the impact on patient-centered outcomes of alternative healthcare delivery models—such as telehealth—that are being implemented in response to COVID-19? What has been learned about barriers and facilitators to their effective implementation?
  • Impact of COVID-19 on vulnerable populations. What are effective clinical pathways to improve outcomes for the most vulnerable and higher risk patients? What are effective system- or organizational-level responses to prevent or mitigate the impact of COVID-19 in low-income and low-resource settings that serve vulnerable populations?
  • Impact of COVID-19 on healthcare workforce well-being, management, and training. What policies, practices, or programs are effective in helping health systems quickly shift human resources, redeploy healthcare workers, and train current and new healthcare workers to fill certain healthcare delivery needs? What are effective strategies to protect the physical and/or mental well-being of the healthcare workforce?

PCORI will fund small studies of up to $2.5 million and large studies of up to $5 million under this Targeted PFA. Under our accelerated timeline, we will announce awards in July.

About These PCORI Funding Announcements

COVID-19 Targeted PFA
Letter of Intent Deadline: None — Application Deadline: May 26

Observational Analyses of Second-Line Pharmacological Agents in Type 2 Diabetes
Letter of Intent Deadline: June 2 — Application Deadline: September 1

Limited Competition PFA: Conducting Rare Disease Research using PCORnet®
Letter of Intent Deadline: June 2 — Application Deadline: September 1

Implementation of Effective Shared Decision Making Approaches in Practice Settings
Letter of Intent Deadline: June 18 — Application Deadline: August 31

Limited Competition PFA: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results
Letter of Intent Deadline: June 18 — Application Deadline: August 31

PFAs on Diabetes, Rare Diseases Also Launched

In addition to the COVID-19 Targeted PCORI Funding Announcement (PFA), we are accepting applications today for two funding opportunities under our more traditional timeline: Observational Analyses of Second-Line Pharmacological Agents in Type 2 Diabetes and Conducting Rare Disease Research using PCORnet®. Both PFAs have a Letter of Intent deadline of June 2; applicants who are invited to submit a full proposal will then have until September 1.

Because of the emergence of a new class of medications—such as SGLT2 inhibitors and GLP-1 receptor agonists—to treat type 2 diabetes mellitus (T2DM), PCORI looks to fund studies that compare the effectiveness of these newer agents versus older second-line pharmacological agents in T2DM among individuals at moderate cardiovascular risk.

While a large-scale randomized controlled trial on this topic would be desirable, it would be time- and resource-intensive. We believe that methodologically robust observational studies that emulate a randomized trial—while not a substitute for clinical trials—have the potential to provide evidence to inform clinical decision making over the short term. We are offering up to $20 million in funding under this PFA, with awards of up to $4 million each in direct costs.

The rare disease PFA is limited to current awardees of PCORnet®, the National Patient-Centered Clinical Research Network. The funding opportunity aims to answer important research questions about the care of patients with rare diseases, but it also looks to enhance the capabilities for multisite rare disease research by creating partnerships, methods, tools, and linkages that will facilitate future comparative effectiveness studies for the rare disease community. PCORnet is uniquely positioned to facilitate the formation of these relationships. We are offering up to $25 million in funding under this PFA, with awards of up to $3.5 million each in direct costs.

Regular Funding Cycles Continue

In addition to these three PFAs, which are in response to unique health challenges facing the nation, our regular work continues. Today we began accepting applications for the implementation of shared decision making approaches and for projects that work to implement PCORI-funded research results into clinical practice under their respective regular funding cycles.

PCORI will continue to balance meeting the needs of the current health pandemic with continuing its core work to fund projects that give patients and those who care for them information to make better-informed healthcare choices. Continue to check back for further developments.

Comments

Firstly, a bunch of thanks

V tight gel May 12, 2020 7:04 am

Permalink

Firstly, a bunch of thanks for sharing such valuable information with us. Actually, I was doing research about the latest update from PCORI & opportunities to take over the market. And i get landed over your article, it was too informative.

Thank you

  • reply

Very interested

Janice Cotton May 15, 2020 12:42 pm

Permalink

Very interested

  • reply

Add new comment

The content of this field is kept private and will not be shown publicly.

More information about text formats

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Topics

Funding Awards
Research

About Us

  • Our Programs
  • Governance
  • Financials and Reports
  • Procurement Opportunities
  • Our Staff
  • Our Vision & Mission
  • Contact Us

Research & Results

  • Explore Our Portfolio
  • Research Fundamentals
  • Research Results Highlights
  • Putting Evidence to Work
  • Peer Review
  • Evidence Synthesis
  • About Our Research

Engagement

  • The Value of Engagement
  • Engagement in Health Research Literature Explorer
  • Influencing the Culture of Research
  • Engagement Awards
  • Engagement Resources
  • Engage with Us

Funding Opportunities

  • What & Who We Fund
  • What You Need to Know to Apply
  • Applicant Training
  • Merit Review
  • Awardee Resources
  • Help Center

Meetings & Events

April 12
Engagement Awards 2021 Special Cycle -- Applicant Office Hours (Three)
April 13
Board of Governors Meeting: April 13, 2021
April 19
Increasing Vaccine Confidence among Long-Term Care Workers: Expedited COVID-19 PFA -- Applicant Town Hall

PCORI

Footer contact address

Patient-Centered Outcomes
Research Institute

1828 L Street, NW, Suite 900
Washington, DC 20036
Phone: (202) 827-7700 | Fax: (202) 355-9558
info@pcori.org

Subscribe to Newsletter

Twitter Facebook LinkedIn Vimeo

© 2011-2021 Patient-Centered Outcomes Research Institute. All Rights Reserved.

Privacy Policy | Terms of Use | Trademark Usage Guidelines | Credits | Help Center