- 2023 Annual Meeting
- The PCORI Strategic Plan
- Clinical Effectiveness and Decision Science
- Dissemination and Implementation
- Evaluation and Analysis
- Healthcare Delivery and Disparities Research
- PCOR Infrastructure & Innovation
- Our Vision & Mission
- Financial Statements and Reports
- The PCORI Strategic Plan
- Board of Governors
- Methodology Committee
- Authorizing Law
- Evaluating Our Work
- PCORI's Advisory Panels
- Procurement Opportunities
Past Opportunities to Provide Input
- Stakeholder Views on Components of 'Patient-Centered Value' in Health and Health Care (2023)
- PCORI's Proposed Research Agenda (2021-2022)
- Proposed National Priorities for Health (2021)
- Proposed Principles for the Consideration of the Full Range of Outcomes Data in PCORI-Funded Research (2020)
- Proposed New PCORI Methodology Standards (2018)
- Data Access and Data Sharing Policy: Public Comment (2017)
- Proposed New PCORI Methodology Standards (2017)
Comment on the Proposed New and Revised PCORI Methodology Standards (2016)
- 1. Standards for Formulating Research Questions
- 10: Standards for Studies of Diagnostic Tests
- 12. Standards on Research Designs Using Clusters
- 13: General Comments on the Proposed Revisions to the PCORI Methodology Standards
- 2: Standards Associated with Patient-Centeredness
- 3: Standards for Data Integrity and Rigorous Analysis
- 4: Standards for Preventing and Handling Missing Data
- 5: Standards for Heterogeneity of Treatment Effects
- 6: Standards for Data Registries
- 7: Standards for Data Networks as Research-Facilitating Structures
- 8. Standards for Causal Inference Methods
- 9. Standards for Adaptive Trial Designs
- Peer-Review Process Comments (2014)
- Draft Methodology Report Public Comment Period (2012)
- Past Opportunities to Provide Input
With each of PCORI’s research funding cycles we have a unique opportunity to improve our process for supporting studies that will provide patients, caregivers, and their clinicians with evidence-based information to improve healthcare decision making and outcomes.
For our upcoming Fall* 2015 cycle, for example, we’re adding a process to further encourage submission of applications that will result in scientifically rigorous comparative clinical effectiveness research (CER) that is truly patient-centered. PCORI staff will invite selected applicants who were not funded during the Fall 2014 cycle to resubmit revised applications. We want to encourage those applicants who seem to understand PCORI’s goals and whose proposals weren’t far off the mark.
We’ll choose high-quality applications that were responsive to our national research priorities, but for which the merit reviewers and PCORI staff raised concerns that seem remediable. Staff will recommend revisions to the selected applicants and discuss options with them. Those invited to resubmit will not be asked to provide the Letter of Intent (LOI) required of other applicants.
Competitive Letters of Intent
Beginning with the Fall 2014 cycle, all applicants—new and resubmitting—have been required to submit a competitive LOI for review by PCORI staff. Only applicants whose LOIs are deemed responsive to the criteria detailed in the relevant PCORI Funding Announcement (PFA) were invited to submit a full application.
In Fall* 2015 and future cycles, those applicants invited to resubmit their applications from an earlier cycle will bypass the competitive LOI review stage. Instead, by the LOI deadline, they will be required to upload their invitation to resubmit, and, if applicable, an email from PCORI program staff indicating approval of any changes to specific aims negotiated during discussions with staff. Applicants who are invited to resubmit must provide their full application by the application deadline specified in the PFA.
All applications submitted or resubmitted to PCORI must adhere to the requirements outlined in the relevant PFA and undergo our rigorous merit review process. And even with this new process, it’s important to note an invitation to resubmit is not a guarantee that the application will move beyond the initial stage of merit review or be selected for funding.
Previous applicants not invited by PCORI staff to resubmit may still resubmit by providing an LOI by the LOI deadline during the Spring 2015 or later cycles. Resubmitted LOIs will be evaluated through the same screening process as newly submitted LOIs.
All applicants who resubmit, either with an LOI or full application through the new process, must include a three-page resubmission statement for the reviewers. To move forward in the review process, all LOIs and applications must meet our review criteria, including patient-centeredness, methodological rigor, and programmatic responsiveness.
We are looking forward to implementing the new resubmission policy and are always available to help answer your questions. Please submit any questions to [email protected].
Tafari is an Associate Director of PCORI’s Research Integration and Evaluation program
Marschhauser is a Merit Review Officer in PCORI’s Research Integration and Evaluation program
* Editor’s note: Earlier versions of this post said “Spring 2015,” but this has been changed to Fall 2015 to reflect merit review timelines.
What's Happening at PCORI?
The Patient-Centered Outcomes Research Institute sends weekly emails about opportunities to apply for funding, newly funded research studies and engagement projects, results of our funded research, webinars, and other new information posted on our site.