PCORI's Investment in Pain Care and Opioids Research
PCORI has invested $252 million in 65 patient-centered comparative clinical effectiveness research studies related to either noncancer pain management or opioid use in an effort to fill in those knowledge gaps. These include 12 studies specifically focused on opioid use.
Some of these studies are comparing different therapies to determine what’s most effective in treating acute and chronic pain. Others are assessing what works best for preventing unsafe opioid prescribing, reducing opioid reliance, and preventing and treating opioid use disorders, among other crucial questions. These studies will provide information on the types of interventions that may be particularly effective in specific patient populations and settings, not just on which approaches work generally.
We are also in the process of evaluating proposals for studies that aim to assess medicated-assisted treatment delivery for pregnant women with opioid use disorders. We anticipate announcing awards for meritorious projects this spring.