1. Overall impressions: it will be more difficult, with these new standards, to justify and use usual care as a comparator in studies that implement population level, pragmatic trials, interventions.

2. We will be proposing studies using usual care as comparator. As stated above, we are less confident than before that we will be able to meet the requirements of the standards. If these standards were applied, we would be less likely to propose a pragmatic study that uses a usual care comparator for a PCORI funding opportunity.

3. All listed components should be best practices, and not requirements.
Anonymous
Researcher, health/medical
Representing my own views