The PCORI Health Care Horizon Scanning System (HCHSS) conducts horizon scanning of new and emerging health care technologies and innovations with high potential for disruption to the current standard of care to better inform patient-centered outcomes research investments at PCORI.

The HCHSS provides PCORI with a systematic process to identify and monitor technologies and innovations in health care that are in PCORI’s priority areas of interest and to create an inventory of interventions that have the highest potential for disruption to the current standard of care in terms of patient outcomes, health disparities, care delivery, infrastructure, access, and/or costs. It will also be a tool for the public to identify information on selected new health care technologies and interventions. Any investigator or funder of research will be able to use the PCORI HCHSS to help select research topics.

The PCORI HCHSS produces quarterly Status Reports, which summarize key data elements for all topics currently monitored in the system and, if applicable, topics archived since the last Status Report.

This report covers 321 topics that represent 240 diseases and conditions. They are organized into 7 sections—one for each of the five initial PCORI-defined priority areas, one for potentially disruptive trends and one for COVID-19-related topics and trends—and titled as follows: (1) Alzheimer’s Disease and Other Dementias, (2) Cancer, (3) Cardiovascular Diseases, (4) Mental and Behavioral Health, (5) Rare Diseases, (6) Potentially Disruptive Trends, and (7) COVID-19.

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