Letters of Intent (LOIs) for the following Cycle 1 2023 Research
PCORI Funding Announcements (PFAs) are due February 7 by 5:00 pm ET.

 

Prevention, Early Identification, and Treatment of Delirium in Older Adults


This PFA is soliciting applications for comparative clinical effectiveness research (CER) studies that focus on the prevention, early identification, and treatment of delirium in older adults. Proposals should focus on one or more of the following three research areas that encompass real-world challenges within delirium research: (1) Prevention (2) Early Identification (3) Treatment.

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Brief Interventions for Adolescent Alcohol Use


This PFA is soliciting applications for comparative clinical effectiveness research (CER) studies that compare brief interventions to address adolescent alcohol use in schools, primary care, or other community-based settings. Proposals should respond to this question: What is the comparative effectiveness of brief behavioral interventions, adapted for adolescents ages 12-17, to address alcohol use?

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Broad Pragmatic Studies


This PFA is soliciting applications for comparative clinical effectiveness research (CER) studies that align with at least one of PCORI's National Priorities for Health. For this 2023 standing PFA, eight topic themes have also been introduced and applicants have the option to choose up to three topic themes, based on how their proposed research aligns with the themes.

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Improving Methods for Conducting Patient-Centered Outcomes Research


Through this PFA, PCORI is seeking to fund studies that address high-priority methodological gaps in patient-centered outcomes research (PCOR) and CER, as well as projects that address important methodological gaps and lead to improvements in the strength and quality of evidence generated by PCOR/CER studies. The PFA includes four areas of programmatic priorities.

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Partnering Research and Community Organizations for Novel Health Equity Research: Addressing Health Systems Factors and Social Determinants of Maternal Health


This PFA focused on improving maternal outcomes by simultaneously addressing health conditions and social determinants of health. It will also uniquely position community organizations to be a full partner and co-lead the project alongside research organizations.

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Advancing the Science of Engagement


The PFA is seeking to fund studies that build an evidence base on engagement in research, including measures to capture structure/context, process, and outcomes of engagement in research; techniques that lead to effective engagement in research; how these techniques should be modified and resourced for different contexts, settings, and communities to ensure equity in engagement and research; and how engagement supports successful research, thereby advancing PCORI's National Priorities for Health.

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