PCORI held an information-rich webinar on the Cycle 2 2024 Addressing Rare Diseases Topical PCORI Funding Announcement, which seeks to fund high-quality patient-centered comparative clinical effectiveness research (CER) projects focused on rare diseases.

Key Dates

  • PFA Opens
    May 7, 2024
  • Letter of Intent (LOI) Deadline
    June 4, 2024; 5 pm (ET)
  • LOI Status Notification
    July 2, 2024
  • Application Deadline
    Sept. 4, 2024; 5 pm (ET)
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During this 60-minute webinar, PCORI walked through:

  • PCORI overview, including what CER and CER-related projects we fund
  • Details of this funding announcement, including both programmatic and administrative requirements
  • Unique requirements for patient and stakeholder engagement
  • PCORI’s Merit Review process
  • Application process and eligibility criteria
  • Applicant resources PCORI offers, including ones specific to writing your LOI, submitting your application and required application templates

Additionally, PCORI Program Officers were on hand to answer your most pressing questions. This town hall is well-suited for: health researchers and scientists, healthcare professionals, research directors, academic institutions, and other members of the healthcare community.

Note: For investigators interested in applying to this research PFA, we encourage you to reach out to us at sciencequestions@pcori.org regarding your proposal to PCORI. Our Program Officers will be happy to respond or schedule time to discuss.


Location Type
Health Conditions Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Populations Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary