Important things to know when thinking about this evidence
- It is normal for most men to have sexual and urinary problems as they age.
- Men with early stage prostate cancer may have these symptoms because of the cancer or because of the treatment for cancer.
- If a man has problems with sex or urinary problems before treatment, the problems could be worse after treatment.
- Every man is different and may have to make decisions differently based on his age, race, family history, stage of cancer, and overall health.
- These studies only looked at the effects of treatment on quality of life.
- Ask your doctor about other sources of information to learn more about each treatment option.
|1. Given my diagnosis, when do I need to make this decision?
2. What other information should I read, and who can I talk to, to help me make this decision?
3. Are there ways that we can treat the side effects so that they don’t affect my quality of life?
|4. Are there any other side effects of surgery or radiation that I should be aware of?
5. Given my health and history, what are my chances that side effects will improve, like for some of these men?
6. What treatment would you recommend given what I’ve told you matters most to me?
Where does the evidence come from?
Two PCORI-funded studies published in the March 21, 2017 issue of a major medical journal compared the effects of current treatment approaches. You can find the studies using the information below.
- These studies included about 3,600 men.
- Around one out of four men in these studies was a member of a racial or ethnic minority group.
- The treatments in these studies were up-to-date approaches to surgery and radiotherapy used today.
PCORI produced this Evidence Update in collaboration with the Urology Care Foundation, Men's Health Network, and American Society of Radiation Oncology.
- Barocas DA, Alvarez J, Resnick MJ, et al. Association Between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes After 3 Years. JAMA. 2017;317(11):1126–1140.
- Chen RC, Basak R, Meyer A, et al. Association Between Choice of Radical Prostatectomy, External Beam Radiotherapy, Brachytherapy, or Active Surveillance and Patient-Reported Quality of Life Among Men With Localized Prostate Cancer. JAMA. 2017;317(11):1141–1150.
The information in this publication is not intended to be a substitute for professional medical advice. This update summarizes findings from PCORI research awards to Vanderbilt University and The University of North Carolina at Chapel Hill.