Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 51 - 75 of 608 results

Project Title
Project Status
Project Type
Has Results

Using PCORnet to Monitor Provider and Patient Risk Factors Related to the Opioid Epidemic

REACHnet CDRN
| Louisiana
Kristin Lyman, JD, MHA
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research Infrastructure
Has Results

Testing Methods to Link Health Data while Protecting Patient Privacy

Indiana University
| Indiana
Shaun Grannis, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Designing and Testing a Search Engine for Clinical Notes Included in Electronic Health Records

Nationwide Children's Hospital/The Ohio State University
| Ohio
Yungui Huang, PhD, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Treat Youth with Anxiety or Obsessive-Compulsive Disorder (OCD)

Emma Pendleton Bradley Hospital
| Rhode Island
Jennifer Freeman, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Testing a Standard Approach to Match Patients with Addiction to Treatment Based on Their Needs -- The PCAST Study

RTI International
| North Carolina
Tami L. Mark, PhD, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Decision Aid Help Older Adults with Chronic Kidney Disease Choose Treatment? -- The DART Study

Trustees of Tufts College
| Massachusetts
Keren Ladin, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Hair Removal Treatments for Adolescents and Young Adults with Pilonidal Disease

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Meditation versus Medicine for Patients with Anxiety Disorders

Georgetown University Medical Center
| District of Columbia
Elizabeth Hoge, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Train Healthcare Clinic Staff to Ask Patients about Sexual Orientation and Gender Identity

Fenway Community Health Center
| Massachusetts
Kenneth H. Mayer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Treat Insomnia among Black Women

Boston University
| Massachusetts
Lynn Rosenberg, ScD, MS, and Eric Zhou, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using PCORnet to Understand Diabetes Medicine Prescribed to Patients

Mid-South CDRN
| Tennessee
Russell Rothman, MD, MPP
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research Infrastructure
Has Results

Evaluating the Safety of Direct-Acting Antivirals for Treating Hepatitis C

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Elizabeth McGlynn, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using PCORnet to Understand PCSK9 Inhibitor Use among Patients at Risk for Heart Disease

University of Florida Board of Trustees
| Florida
Rhonda Cooper-DeHoff, PharmD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research Infrastructure
Has Results

Using PCORnet to Understand Use of Molecular Tests and Treatments for Cancerous Tumors

University of Kansas Medical Center (GPC CDRN)
| Kansas
Russ Waitman, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research Infrastructure
Has Results

Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update

Memorandum of Understanding with Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Completed
Project Type:
Research
Has Results

Nonsurgical Treatments for Urinary Incontinence in Women: A Systematic Review Update

Memorandum of Understanding with Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Completed
Project Type:
Research
Has Results

Psychological and Pharmacological Treatments for Adults with Posttraumatic Stress Disorder (PTSD): A Systematic Review Update

Memorandum of Understanding with Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Completed
Project Type:
Research
Has Results

Stroke Prevention in Atrial Fibrillation Patients: A Systematic Review Update

Memorandum of Understanding with Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Completed
Project Type:
Research
Has Results

Evaluating Hormone Treatments for Women at Increased Risk for Preterm Birth -- The EPPPIC Study

University of York (United Kingdom)
| N/A
Lesley Stewart, PhD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using PCORnet to Improve Data Quality and Patient Follow-Up Within the Transcatheter Valve Therapy Registry

Mayo Clinic
| Minnesota
Maurice E. Sarano, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing a Multiple Sclerosis Fatigue Management Course Delivered via Teleconference, Internet, or in Person

Case Western Reserve University
| Ohio
Matthew A. Plow, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Examining Whether Early Aggressive Therapy Can Prevent or Delay Disability in People with Multiple Sclerosis: the TREAT-MS Study

Johns Hopkins University
| Maryland
Ellen M. Mowry, MD, MCR
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effectiveness of Three Treatments for Reducing Fatigue among Patients with Multiple Sclerosis -- The COMBO-MS Trial

University of Michigan
| Michigan
Tiffany J. Braley, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Antiseptic Skin Solutions to Prevent Infection in Patients Having Surgery to Treat Fractures -- The PREPARE Study

University of Maryland, Baltimore
| Maryland
Gerard P. Slobogean, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

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