Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 24 of 24 results

Project Title
Project Status
Project Type

Preventing Suicidal Behavior with Diverse High-Risk Youth in Acute Care Settings

Johns Hopkins University
| Maryland
Holly Wilcox, PhD, MA
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Ways to Prevent Falls among Patients with Cirrhosis of the Liver

University of Michigan
| Michigan
Elliot Tapper, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Four Ways to Treat Opioid Use Disorder

Philadelphia College of Osteopathic Medicine
| Pennsylvania
Michelle Lent
Project Status:
In progress; Recruiting
Project Type:
Research

Does a Counseling Program for Friends and Family Help People with Opioid Use Disorder Stay in Treatment?

Stanford University
| California
Karen Osilla, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat Insomnia in Adults Living in Rural Areas

Sutter Bay Hospital
| California
Katie Stone, PhD, MA
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Essure® and Tubal Ligation to Prevent Pregnancy

Yale University
| Connecticut
Aileen M. Gariepy, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Physical Therapy Schedules for Children with Cerebral Palsy -- The ACHIEVE Study

The Ohio State University
| Ohio
Jill C. Heathcock, MPT, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Treatment Approaches for Women with Ductal Carcinoma In Situ (DCIS) -- The PORTAL Study

Duke University
| North Carolina
E. Shelley Hwang, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of Different Surgical Treatments on Quality of Life for Patients with Obesity

Massachusetts General Hospital
| Massachusetts
Matthew Hutter, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Bladder Management Strategies for People with Spinal Cord Injuries

University of Utah
| Utah
Jeremy Myers, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Assessing Support for Medicine Decision Making for Youth with ADHD Who Receive Therapy

CASAColumbia
| New York
Aaron Hogue, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of Different Prostate Cancer Treatments on Quality of Life and Cancer Recurrence -- NC ProCESS

University of North Carolina at Chapel Hill
| North Carolina
Ronald C. Chen, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Peer Support Program That Helps Older Adults Age in Their Own Homes

University of Wisconsin–Madison
| Wisconsin
Elizabeth A. Jacobs, MD, MPP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does Information on Benefits and Risks Help Patients Decide Between Stent Options?

University of Missouri Kansas City
| Missouri
John Spertus, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Physical Therapy, Internet-Based Exercise Training, and No Therapy for Knee Osteoarthritis

University of North Carolina Chapel Hill^
| North Carolina
Kelli D. Allen, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Effects of Maternal Depression and Its Treatment on Infant Health in Pregnant Women, with or without Other Mental Illness

Kaiser Foundation Research Institute
| California
De-Kun Li, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Hematopoietic Cell Transplant versus Other Treatments for Adults with Acute Myeloid Leukemia

Fred Hutchinson Cancer Research Center
| Washington
Mohamed Lotfy Sorror, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Treatments for Aortic Valve Disease

Duke University
| North Carolina
J. Matthew Brennan, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Coordinated-Care Management Approach Improve Care and Health for Patients with a Sleep Disorder? -- SMART DOCS

Stanford University School of Medicine
| California
Clete Kushida, MD, MS, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of Surgery, Radiation Therapy, and Active Surveillance on Men with Localized Prostate Cancer -- The CEASAR Study

Vanderbilt University
| Tennessee
David Penson, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Recovery Options for Stroke Patients

Duke University
| North Carolina
Janet Prvu Bettger, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Nonsurgical Treatments for Lumbar Spinal Stenosis in Reducing Pain and Increasing Walking Ability

University of Pittsburgh
| Pennsylvania
Michael J. Schneider, DC, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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