Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 22 of 22 results

Project Title
Project Status
Project Type

Comparing Two Therapies for Improving Social and Thinking Skills in Patients with Schizophrenia

Beth Israel Deaconess Medical Center, Inc
| Massachusetts
Matcheri S. Keshavan, MD, and Russell K. Schutt, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Hair Removal Treatments for Adolescents and Young Adults with Pilonidal Disease

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing the Effects of Three-Week versus Five-Week Courses of Radiation Therapy for Women with Breast Cancer Getting Mastectomy with Breast Reconstruction

Dana-Farber Cancer Institute
| Massachusetts
Rinaa Sujata Punglia, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Understanding How Patients' Response to Treatment Varies Using Predicted Risk

Tufts Medical Center, Inc.
| Massachusetts
David Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding How to Use Single Patient Studies to Answer Patient-Identified Research Questions

Cincinnati Children’s Hospital Medical Center
| Ohio
Heather C. Kaplan, MD, MSCE; Lisa Opipari-Arrigan, PhD; Gregory M. Marcus, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Physical Therapy Schedules for Children with Cerebral Palsy -- The ACHIEVE Study

The Ohio State University
| Ohio
Jill C. Heathcock, MPT, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Antibiotics and Surgery to Treat Appendicitis in Children

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Increase Physical Activity in Patients with Depression and Cardiovascular Disease -- The Healthy Hearts Healthy Minds Study

Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effects of Different Surgical Treatments on Quality of Life for Patients with Obesity

Massachusetts General Hospital
| Massachusetts
Matthew Hutter, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Clinician-Collected and Self-Collected Tests for Detecting High-Risk HPV Infection among Female-to-Male Transgender Adults

Fenway Community Health Center
| Massachusetts
Sari Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Restrictive Diets for Treating Eosinophilic Esophagitis in Children

Cincinnati Children's Hospital Medical Center
| Ohio
Marc Rothenberg, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Monitoring Oxygen Levels of Premature Babies at Home and in the Clinic -- The RHO Trial

University of Massachusetts Medical School^
| Massachusetts
Lawrence Rhein, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Evaluating Two Rehab Approaches for Patients with Traumatic Brain Injury

Ohio State University College of Medicine
| Ohio
Jennifer A. Bogner, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Can an Online Program Help Women with a History of Preeclampsia Reduce Their Risk of Heart Disease?

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Janet Rich-Edwards, MPH, ScD, and Ellen W. Seely, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Improving Informed Consent for Palliative Chemotherapy

Dana-Farber Cancer Institute
| Massachusetts
Deborah Schrag, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Including Patient Traits in Benchmarks for Diabetes Care

Harvard University School of Public Health
| Massachusetts
Marcia Anne Testa, BA, MPH, MPHIL, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Online and In-Person Family Therapy for Teens with Traumatic Brain Injury and Their Parents

Cincinnati Children's Hospital Medical Center
| Ohio
Shari L. Wade, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Helping Caregivers and Their Children with Early Appendicitis Make Treatment Decisions with an App

The Research Institute at Nationwide Children's Hospital
| Ohio
Katherine Deans, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Surgical Treatments for Cervical Spondylotic Myelopathy -- The CSM-S Trial

Lahey Clinic, Inc.
| Massachusetts
Zoher Ghogawala, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Which Treatments for Uterine Fibroids Have the Best Results?

Outcome Sciences
| Massachusetts
Priscilla Velentgas, MS, PhD*
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Predicting the Impact of Treatment Options on Survival and Breast Conservation in Patients with Ductal Carcinoma In Situ (DCIS)

Dana-Farber Cancer Institute
| Massachusetts
Rinaa Punglia, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Predicted Benefits and Harms of Using Adult versus Child Guidelines for Lipid Testing and Treatment in 17- to 21-Year-Olds

Tufts Medical Center, Inc.
| Massachusetts
Laurel K. Leslie, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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