Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 221 results

Project Title
Project Status
Project Type

Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment

Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
In progress; Recruiting
Project Type:
Research

A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Help Patients Control High Blood Pressure

Brody School of Medicine at East Carolina University
| North Carolina
Doyle Cummings, PharmD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Screen People for Anxiety, Substance Use Disorders, and Intimate Partner Violence before and after Giving Birth -- The LTWP Study

Medical University of South Carolina
| South Carolina
Constance Guille, MD, MSCR
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Prevent Falls among Patients with Cirrhosis of the Liver

University of Michigan
| Michigan
Elliot Tapper, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Individualizing Treatment for Asthma in Primary Care

DARTNet Institute
| Kansas
Wilson Pace, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Healthcare Visit Recording and Open Notes to Improve the Chronic Illness Care Experience for Older Adults (The CHRONICLE Trial)

Trustees of Dartmouth College
| New Hampshire
Paul Barr, PhD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Effectiveness of a Multimodal Intervention for Transitions of Care after Lower Limb Fracture

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Patricia Dykes, PhD, RN, MA
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparing Two Ways to Help Children with Complex Chronic Diseases Return Home after a Hospital Stay -- The GET2HOME Study

Cincinnati Children's Hospital Medical Center
| Ohio
Patrick Brady, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Efficacy of Pharmacologic Management of ADHD in Children and Youth with Autism Spectrum Disorder

The Research Institute at Nationwide Children's Hospital
| Ohio
Daniel Coury, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Can Pharmacists Support Primary Care Providers as Well as Pulmonologists in Treating Patients with COPD? -- The EQuiP COPD Study

VA Puget Sound Health Care System
| Washington
David Au, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Urgency Urinary Incontinence in Women -- The BEST Trial

Women and Infants Hospital-Rhode Island
| Rhode Island
Vivian Sung, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Tailoring Incontinence Care: OnabotulinumtoxinA for Urgency Urinary Incontinence Among Older Women

Dartmouth-Hitchcock Clinic
| New Hampshire
Anne Cooper, MD, MA
Project Status:
In progress; Recruiting
Project Type:
Research

Community-Based, Family-Centered, Trauma-Informed Approach to Timely Detection and Management of Early Postpartum Hypertension

Yale School of Public Health
| Connecticut
Rafael Perez-Escamilla, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Help People Quit Smoking

University of Florida
| Florida
Jesse Dallery, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Online Programs for Treating Chronic Pain -- The PROGRESS Study

Stanford University
| California
Beth Darnall, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Types of Medicine for Pain after Surgery -- The CARES Trial

University of Michigan
| Michigan
Mark Bicket MD, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Screening Tests for Colon Cancer in Older Adults with a History of Colon Polyps -- The COOP Study

Dartmouth-Hitchcock Clinic
| New Hampshire
Audrey Calderwood, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Suicide Prevention Programs for Young People following an ER Visit

University of California, Los Angeles
| California
Joan Asarnow, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Prevent Suicide among Alaska Native Young People -- The BeWeL Study

RAND Corporation
| Pennsylvania
Elizabeth D'Amico, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Four Ways to Reduce Pregnancy Complications among Black Mothers -- The ACURE4Moms Study

University of North Carolina at Chapel Hill School of Medicine
| North Carolina
Jennifer Tang, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Telehealth to In-Person Crisis Prevention for Youth with Intellectual and Developmental Disabilities

University System of New Hampshire
| New Hampshire
Joan Beasley, PhD, MEd
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Improve Mental Health among Youth with Disabilities -- The BEST Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Improve COVID-19 Vaccination Rates at Long-Term Care Centers -- The ENSPIRE Study

Kaiser Foundation Health Plan of Washington (Kaiser Permanente Washington Health Research Institute)
| California
Clarissa Hsu, PhD, MA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Monitor and Treat High Blood Pressure in Children with Chronic Kidney Disease -- The PRESERVE Study

Children's Hospital of Philadelphia
| Pennsylvania
Christopher Forrest, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

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