Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 29 results

Project Title
Project Status
Project Type

Comparing Two Online Programs for Treating Chronic Pain -- The PROGRESS Study

Stanford University
| California
Beth Darnall, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Does Treating Genital Herpes in Pregnancy Reduce Racial Disparities in Severe Maternal Morbidity? -- The PCORI SMM Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
De-Kun Li, MD, MPH, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Reduce Flare-Ups among People with Inflammatory Bowel Disease -- The QUOTIENT Study

University of California San Diego
| California
Siddharth Singh, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Patients with Rheumatoid Arthritis -- The RA-PRO PRagmatic Trial (RA-PROPR)

The University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Increase HPV Testing for Cervical Cancer Screening

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Chun Chao, PhD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

What Is the Effect of Adding a Health Coach to Patient-Centered Medical Homes for Managing Multiple Chronic Conditions?

Clinical Directors Network
| New York
Jonathan Tobin, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Strategies for Health Clinics to Increase HPV Vaccinations in Youth

UCLA School of Public Health
| California
Roshan Bastani, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain

RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Home- Versus Clinic-Based Phototherapy for the Treatment of Psoriasis -- The LITE Study

University of Pennsylvania
| Pennsylvania
Joel Mitchell Gelfand, MD, MS
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Treatments to Help Patients with Head and Neck Cancer Address Problems with Swallowing

University Health Network (Canada)
| N/A
Rosemary Martino, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Two Medicines for Adults with Myasthenia Gravis -- The PROMISE-MG Study

Duke University
| North Carolina
Donald B. Sanders, MD, and Pushpa Narayanaswami, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Engaging Patients and Providers in Collaborative Communication on HPV Vaccination (EPPIC-HPV)

University of New Mexico Main Campus
| New Mexico
Gill Woodall, PhD
Project Status:
Terminated
Project Type:
Research
Has Results

Does Treating Genital Herpes during Pregnancy Improve Birth Outcomes?

Kaiser Foundation Research Institute
| California
De-Kun Li, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Research Networks to Compare Medicines for Autoimmune and Inflammatory Diseases -- The Comparative Health Outcomes in Immune-mediated diseases CollaborativE (CHOICE) Study

University of Alabama at Birmingham
| Alabama
Jeffrey R. Curtis, MD, MPH, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Stopping or Continuing Use of Disease Modifying Therapies in Older Adults with Multiple Sclerosis -- The DISCOMS Trial

University of Colorado Denver
| Colorado
John R. Corboy, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Programs for Helping Patients Make Informed Decisions about Rheumatoid Arthritis Treatment

The University of North Carolina at Chapel Hill
| North Carolina
Susan Blalock, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Start Treatment for Patients with Polyarticular Juvenile Idiopathic Arthritis -- The STOP-JIA Trial

Hackensack University Medical Center
| New Jersey
Yukiko Kimura, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Clinician-Collected and Self-Collected Tests for Detecting High-Risk HPV Infection among Female-to-Male Transgender Adults

Fenway Community Health Center
| Massachusetts
Sari Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Statistical Methods to Preserve Patient Privacy When Sharing and Analyzing Data

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
Darren Toh, ScD, BPHAR, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

New Statistical Methods to Assess How Patients with Different Traits Respond to the Same Treatment

University of Miami School of Medicine
| Florida
Daniel Feaster, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Having Patients and Providers Identify Meaningful Changes in Rheumatoid Arthritis Symptoms

Johns Hopkins University
| Maryland
Clifton Bingham, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Clinic-Based Program to Reduce Risky Behaviors among Teens

Seattle Children's Hospital
| Washington
Carolyn McCarty, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Ways of Treating Rheumatoid Arthritis When Patients Are in Remission -- The STARA Study

Georgetown University
| District of Columbia
Florina Constantinescu, MD, PhD^
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Ask Patients about Sexual Orientation and Gender Identity in the Emergency Room -- The EQUALITY Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Adil Haider, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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