Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 45 results

Project Title
Project Status
Project Type

Revascularization Choices Among Under-Represented Groups Evaluation (The RECHARGE Program)

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Mario Gaudino, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Annual Wellness Visits versus GRACE-augmented Annual Wellness Visits for Older Adults with High Needs

Massachusetts General Hospital
| Massachusetts
Christine Ritchie, M.D., MSPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Generalist versus Specialist Palliative Care for Inpatients

University of Pennsylvania
| Pennsylvania
Scott Halpern, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Sinusitis

Georgetown University Medical Center
| District of Columbia
Daniel Merenstein, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Pacing Treatments for Patients with Heart Failure

Baylor College of Medicine
| Texas
Mihail G. Chelu, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment

Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Sequential Multiple Assignment Randomized Trial for Bipolar Depression: SMART-BD

Massachusetts General Hospital
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Individualizing Treatment for Asthma in Primary Care

DARTNet Institute
| Kansas
Wilson Pace, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Two Screening Tests for Colon Cancer in Older Adults with a History of Colon Polyps -- The COOP Study

Dartmouth-Hitchcock Clinic
| New Hampshire
Audrey Calderwood, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Palliative Care for Patients Who Are in the Hospital with Acute Myeloid Leukemia

Massachusetts General Hospital
| Massachusetts
Areej El-Jawahri, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Anesthesia for Surgery -- The THRIVE Trial

Regents of the University of Michigan
| Michigan
Sachin Kheterpal, MD, MBA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Control Blood Pressure after Stroke

Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Prevention Programs for Teens at Risk for Suicide

Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Three Programs to Increase Access to Mental Health Care for Pregnant and Postpartum Patients

The Research Foundation for The State University of New York on behalf of State University of New York Downstate Health Sciences University (SUNY DHSU)
| New York
Thomas I. Mackie, PhD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Expanding the Use of a School-Based Program to Improve Executive Functioning among Students with Symptoms of Autism Spectrum Disorder or Attention Deficit/Hyperactivity Disorder

University of Colorado Denver
| Colorado
Laura G. Anthony, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Implementing Team-based Outpatient Palliative Care in Parkinson Foundation Centers of Excellence

University of Rochester
| New York
Benzi M. Kluger, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Establishing a Patient-Led African Immigrant Health Research Consortium

Multicultural AIDS Coalition
| Massachusetts
Chioma Nnaji, MED, MPH
Project Status:
Awarded; In progress
Project Type:
Engagement Award Project

Expanding Access to the Infusion Center Model for People Living with SCD

Johns Hopkins School of Medicine
| Maryland
Sophie Lanzkron, MD, MHS
Project Status:
Awarded; In progress
Project Type:
Engagement Award Project, Dissemination Project

Improving Antibiotic Prescribing in Children with Ear, Sinus, and Throat Infections

The Children's Hospital of Philadelphia
| Pennsylvania
Jeffrey Gerber, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Comparing Two Ways to Treat People with PTSD and Substance Use Disorder -- The COMPASS Study

Center for Veterans Research and Education
| Minnesota
Shannon M. Kehle-Forbes, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Primary Care Treatment Options for People with PTSD

University of Washington
| Washington
John Fortney, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Using the Child Health Ratings Inventories (CHRIS) to Improve Care for Children with Type 1 Diabetes

University of California, Irvine
| California
Sherrie H. Kaplan, PhD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Building Research Capacity on Hearing Loss Interventions in Hispanic/Latinx Communities

University of Arizona
| Arizona
Nicole Marrone, PhD
Project Status:
Awarded; In progress
Project Type:
Engagement Award Project

Helping Adults with Serious Mental Illness Improve Their Health and Wellness

The Rochester General Hospital
| New York
Alise Gintner, LCSW
Project Status:
Awarded; In progress
Project Type:
Engagement Award Project, Dissemination Project

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