Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 128 results

Project Title
Project Status
Project Type
Has Results

Self-Management in Older Adults with Chronic Heart Failure -- The iCOACH Study

University of Arkansas for Medical Sciences
| Arkansas
Judy Weber, PhD, RD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Developing and Testing New Methods for Comparing Outcomes Across Groups of Patients in Observational Studies

Duke University
| North Carolina
Laine E. Thomas, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Provide Enhanced Prenatal Care to Improve Health in Mothers and Babies -- The EMBRACE Study

University of California, San Francisco
| California
Miriam Kuppermann, PhD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Stroke and Blood Clot Risk in Transgender Women Taking Hormones

Emory University
| Georgia
Michael Goodman, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Help Sexual and Gender Minority Men Who Have Been Sexually Abused Reduce Depression and Increase Mental Health Treatment Engagement

Yale University
| Connecticut
Joan M. Cook, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Promote Quitting Smoking for People Referred for Lung Cancer Screenings

University of Pennsylvania
| Pennsylvania
Scott Halpern, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Inpatient Versus Outpatient Settings for Treating Teens after a Suicidal Event

Cincinnati Children's Hospital Medical Center
| Ohio
Drew Barzman, MD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Developing and Testing New Methods for Linking and Analyzing Multiple Data Sources with Limited Patient Identifiers

Brown University
| Rhode Island
Roee Gutman, PhD, MS, BSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Developing and Testing a New Method for Comparing More than Two Treatments Using Electronic Health Records

Rutgers, The State University of New Jersey
| New Jersey
Liangyuan Hu, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Programs to Reduce Unsafe Opioid Prescribing and Improve Outcomes among People Who Are Injured at Work -- The WOW Study

University of Washington
| Washington
Gary Franklin, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Treatments for Depression among Patients with Advanced Heart Failure

Cedars-Sinai Health System
| California
Waguih William IsHak, MD, FAPA
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Ways to Treat Youth with Anxiety or Obsessive-Compulsive Disorder (OCD)

Emma Pendleton Bradley Hospital
| Rhode Island
Jennifer Freeman, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Hair Removal Treatments for Adolescents and Young Adults with Pilonidal Disease

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Treat Insomnia among Black Women

Boston University
| Massachusetts
Lynn Rosenberg, ScD, MS, and Eric Zhou, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing a Multiple Sclerosis Fatigue Management Course Delivered via Teleconference, Internet, or in Person

Case Western Reserve University
| Ohio
Matthew A. Plow, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing the Effectiveness of Three Treatments for Reducing Fatigue among Patients with Multiple Sclerosis -- The COMBO-MS Trial

University of Michigan
| Michigan
Tiffany J. Braley, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Antiseptic Skin Solutions to Prevent Infection in Patients Having Surgery to Treat Fractures -- The PREPARE Study

University of Maryland, Baltimore
| Maryland
Gerard P. Slobogean, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Developing New Randomization Methods for Electronic Health Data Randomization to Conduct Comparative Effectiveness Research

Dartmouth College
| New Hampshire
Tor D. Tosteson, ScD, MS, BA
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Determining Whether Adding a Palliative Care Team Improves Quality of Life for Patients Who Have Had Upper Gastrointestinal Cancer Surgery -- The PERIOP-PC Study

Stanford University^
| California
Karl Lorenz, MD, MSHS^
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Essure® and Tubal Ligation to Prevent Pregnancy

Yale University
| Connecticut
Aileen M. Gariepy, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Decrease Medicine Use for Nursing Home Residents with Dementia

University of Pittsburgh^
| Pennsylvania
Natalie E. Leland, PhD
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research
Has Results

Comparing Two Ways to Treat Depression among Pregnant Women and New Mothers with Low Incomes

Boston Medical Center
| Massachusetts
Michael Silverstein, MD, MPH; Caroline J Kistin, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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