Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 101 - 125 of 258 results

Project Title
Project Status
Project Type

Comparing Strategies to Help People with Traumatic Brain Injury Continue Recovering after a Hospital Stay -- The BRITE Study

University of Washington
| Washington
Jeanne Hoffman, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Support Communication between Patients and Their Primary Care Providers

University of California, San Diego^
| California
Ming Tai-Seale, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Messaging Systems to Increase Use of Online Programs That Help Smokers Quit -- Smoker-to-Smoker (S2S)

University of Massachusetts Medical School
| Massachusetts
Rajani Sadasivam, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Identifying and Treating Childhood Hearing Loss in Rural Alaska -- The Hearing Norton Sound Study

Norton Sound Health Corporation
| Alaska
Samantha Kleindienst Robler, AuD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Approaches to Help Patients and Doctors Talk about Chronic Pain Treatments -- Voices in Pain Care

Cedars-Sinai Medical Center
| California
Brennan Spiegel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Approaches to Help Patients Manage Symptoms at Home after Cancer Surgery -- The ACCESS Study

Memorial Sloan Kettering Cancer Center
| New York
Brett Simon, MD, PhD, and Andrea Pusic, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding How to Use Single Patient Studies to Answer Patient-Identified Research Questions

Cincinnati Children’s Hospital Medical Center
| Ohio
Heather C. Kaplan, MD, MSCE; Lisa Opipari-Arrigan, PhD; Gregory M. Marcus, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effectiveness of Electronic Symptom Monitoring versus Usual Care in Improving Survival among Patients with Metastatic Cancer -- The PRO-TECT Trial

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Ethan Basch, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Ways to Provide Follow-Up Care to Patients after Bone Marrow Transplants

Dana-Farber Cancer Institute
| Massachusetts
Gregory Abel, MD, MPH
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research

Engaging Patients and Providers in Collaborative Communication on HPV Vaccination (EPPIC-HPV)

University of New Mexico Main Campus
| New Mexico
Gill Woodall, PhD
Project Status:
Terminated
Project Type:
Research
Has Results

Comparing Three Ways to Help Patients with Acute Pain Learn about Opioid Risks -- The Life STORRIED Study

University of Pennsylvania
| Pennsylvania
Zachary F. Meisel, MD, MPH, MSHP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Identify Sleep Apnea in People with Traumatic Brain Injury during Inpatient Rehabilitation

Tampa VA Research and Education Foundation
| Florida
Risa Nakase-Richardson, PhD, FACRM, FNAN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Programs to Help Latino Men Lose Weight -- The HOMBRE Trial

Stanford University School of Medicine^
| California
Lisa G. Rosas, MPH, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Help Veterans Manage Chronic Pain -- The VOICE Study

University of Minnesota Twin Cities
| Minnesota
Erin Krebs, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Clinic- and Home-Based Exercise Programs to Help Adults with Multiple Sclerosis -- The TEAMS Study

University of Alabama at Birmingham
| Alabama
James Rimmer, PhD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Improving Methods for Analyzing Data from Case-Only Studies

President & Fellows of Harvard College
| Massachusetts
Murray A. Mittleman, MD, DPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Does a Web-Based Decision Aid Help Patients and Their Doctors Decide How to Treat Hip and Knee Arthritis?

Northwestern University^
| Illinois
Patricia D. Franklin, MD, MBA, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Three Ways to Increase Colorectal Cancer Screening

Indiana University
| Indiana
Susan Rawl, PhD, MS, BSN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Telehealth and Clinic-Based Care for Lowering Uncontrolled High Blood Pressure

HealthPartners Institute
| Minnesota
Karen L. Margolis, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Evaluating a Telehealth Program for Ostomy Self-Care among Cancer Survivors

The Trustees of the University of Pennsylvania^
| Pennsylvania
Robert S. Krouse, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Web-Based Platform for Caregivers Help People with Down Syndrome Get Recommended Health Services?

Massachusetts General Hospital
| Massachusetts
Brian Skotko, MD, MPP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Increase Physical Activity in Patients with Depression and Cardiovascular Disease -- The Healthy Hearts Healthy Minds Study

Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Three Approaches to Improve Diabetes Self-Care among African-American Adults -- The MODEL Study

The University of Tennessee Health Science Center
| Tennessee
James E. Bailey, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Manage Symptoms for Patients Who Have Chronic Migraine and Frequent Medication Use -- The MOTS Trial

Mayo Clinic Arizona
| Arizona
Todd J. Schwedt, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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