Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 176 - 200 of 315 results

Project Title
Project Status
Project Type
Has Results

Creating a New Process to Include Medical Device Information in Insurance Claims

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Joel S. Weissman, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing and Testing New Methods for Estimating Treatment Effectiveness in Observational Studies Using High-Dimensional Data

Rutgers, The State University of New Jersey, New Brunswick
| New Jersey
Zhiqiang Tan, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Linking Randomized Clinical Trials and ClaiTRD Data for Enhancing Randomized and Non-Randomized Patient-Centered Outcomes Evidence Generation

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Mehdi Najafzadeh, PhD, MA, TRD
Project Status:
Awarded; Contract not executed
Project Type:
Research
Has Results

Developing Statistical Methods for Estimating Patient Phenotypes Using Electronic Health Record Data

University of Pennsylvania
| Pennsylvania
Rebecca Hubbard, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Creating a Survey of Community Engagement in Research

Washington University School of Medicine
| Missouri
Vetta Sanders Thompson, PhD, MA^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing New Statistical Methods for Clinical Studies Where Patients Choose Their Treatments

Yale University
| Connecticut
Denise Esserman, MS, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Visual Analytic Methods to Identify Patient Groups

The University of Texas Medical Branch at Galveston
| Texas
Suresh K. Bhavnani, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Medicines to Prevent Blood Clots after Treatment for Fractures -- The PREVENT CLOT Study

University of Maryland Baltimore
| Maryland
Robert V. O'Toole, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Benefits and Harms of Different Long-Term Treatments for Blood Clots -- The DARE Warfarin Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Katsiaryna Bykov, PharmD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment Strategies to Prevent Future Blood Clots among Patients Who Received at Least Three Months of Blood Thinners -- The ALTERNATIVE Study

University of California, San Francisco
| California
Margaret Fang, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Treatment Approaches for Older Adults with Treatment-Resistant Depression -- The OPTIMUM Study

Washington University School of Medicine
| Missouri
Eric J. Lenze, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing ECT and Ketamine in Adults with Treatment-Resistant Depression – The ELEKT-D Study

Cleveland Clinic Foundation
| Ohio
Amit Anand, MD^
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Managing Long-Term Low Back Pain to Improve Health and Reduce Reliance on Opioid Medicines: Comparing Mindfulness Meditation and Cognitive Behavioral Therapy -- Strategies To Assist with Management of Pain (STAMP)

University of Wisconsin-Madison
| Wisconsin
Bruce Barrett
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Help Veterans Manage Chronic Pain -- The VOICE Study

University of Minnesota Twin Cities
| Minnesota
Erin Krebs, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Oral Medicines to Improve Patient Experiences with Relapsing-Remitting Multiple Sclerosis -- PRAG-MS

Fondazione IRCCS Istituto Neurologico "Carlo Besta" (Italy)
| N/A
Renato Mantegazza, MD^
Project Status:
Terminated
Project Type:
Research

Comparing Clinic- and Home-Based Exercise Programs to Help Adults with Multiple Sclerosis -- The TEAMS Study

University of Alabama at Birmingham
| Alabama
James Rimmer, PhD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Different Medicines to Treat Multiple Sclerosis -- The COMBAT-MS Study

Karolinska Institute (Sweden)
| N/A
Fredrik Piehl, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Medicines to Help Patients with Multiple Sclerosis Feel Less Fatigued -- The TRIUMPHANT-MS Study

Johns Hopkins University^
| Maryland
Bardia Nourbakhsh, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Connecting Research to Real Life: Building a Research Network in the Columbia River Gorge - Tier III

Columbia Gorge Family Medicine
| Oregon
Kristen Dillon, MD
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier III

Fostering Successful Aging: Demonstrating the Impact of an Innovative Shared Medical Appointments Model - Tier III

Palo Alto Medical Foundation
| California
Peter H. Cheng, MD, AGSF
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier III

Promoting Patient-Centered Research in the Puget Sound Asthma Coalition - Tier III

Washington State University College of Nursing
| Washington
Julie Postma
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier III

Improving Diabetes Education and Management in Schools: A Community Project - Tier III

Seattle Children's Hospital
| Washington
Joyce Yi-Frazier
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier III

The Patient-Centered Primary Care Council in the Highland Hospital Adult Medicine Clinic: Strengthening Primary Care Together - Tier III

Organization Patient-Centered Primary Care (PCPC) Team, K-6 Adult Medicine Clinic, Highland Hospital"
| California
Irene Yen
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier III

Building the New Mexico LGBTQ Health Improvement Network: Strengthening Community Health through Communication, Connection and Empowerment - Tier III

University of New Mexico Health Sciences Center
| New Mexico
Miria Kano, PhD
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier III

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