Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 17 of 17 results

Project Title
Project Status
Project Type
Has Results

Comparing Ways to Help Primary Care Providers Prescribe Opioids Safely

University of Pittsburgh
| Pennsylvania
Kevin Kraemer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Medicines for Adults with Myasthenia Gravis -- The PROMISE-MG Study

Duke University
| North Carolina
Donald B. Sanders, MD, and Pushpa Narayanaswami, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Programs to Treat Opioid Use Disorder in Primary Care and Substance Use Clinics

Public Health Management Corporation^
| Pennsylvania
David R. Gastfriend, MD
Project Status:
Terminated
Project Type:
Research

Comparing Three Medicines to Prevent Blood Clots in Patients Who Need Long-Term Blood-Thinning Treatment -- The COVET Trial

Duke University
| North Carolina
Thomas L. Ortel, MD, PhD
Project Status:
Terminated
Project Type:
Research
Has Results

Comparing Cognitive Behavioral Therapy versus Yoga for Helping Older Adults Address High Levels of Worry

Wake Forest University
| North Carolina
Gretchen A. Brenes, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Treatment Approaches for Women with Ductal Carcinoma In Situ (DCIS) -- The PORTAL Study

Duke University
| North Carolina
E. Shelley Hwang, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Low-Dose versus High-Dose Aspirin to Prevent Problems from Heart Disease -- The ADAPTABLE Study -- A PCORnet® Study

Duke University
| North Carolina
William Schuyler Jones, MD*
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

A Training Program on Pain Coping Skills for African Americans with Hip or Knee Arthritis

The University of North Carolina at Chapel Hill
| North Carolina
Kelli Allen, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Helping People with Opioid Use Disorders Avoid Relapses after Leaving Jail

University of Pennsylvania
| Pennsylvania
George Woody, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Changes in Health for Patients Who Complete Treatment for Chronic Hepatitis C Virus -- The PROP up TARGET Study

The University of North Carolina at Chapel Hill
| North Carolina
Donna Evon, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Types of Anesthesia for Hip Fracture Surgery -- The REGAIN Trial

University of Pennsylvania
| Pennsylvania
Mark D. Neuman, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Graphic Novels when Choosing Treatment for Alcohol Use Disorder

Public Health Management Corporation^
| Pennsylvania
Adam Brooks, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Broad- and Narrow-Spectrum Antibiotics for Children with Ear, Sinus, and Throat Infections

The Children's Hospital of Philadelphia
| Pennsylvania
Jeffrey Gerber, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Anti-TNF Drugs versus Long-Term Steroid Use for Patients with Inflammatory Bowel Diseases

University of Pennsylvania
| Pennsylvania
James Lewis, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Different Medicines for People Who Have Had a Stroke -- The PROSPER Study

Duke University
| North Carolina
Adrian F. Hernandez, MD, MHS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

For Children Discharged after Hospitalization for Serious Bacterial Infections, Are Orally Administered Antibiotics as Effective as Antibiotics Given Intravenously through a PICC?

The Children's Hospital of Philadelphia
| Pennsylvania
Ron Keren, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Nonsurgical Treatments for Lumbar Spinal Stenosis in Reducing Pain and Increasing Walking Ability

University of Pittsburgh
| Pennsylvania
Michael J. Schneider, DC, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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