Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 21 of 21 results

Project Title
Project Status
Project Type

Comparing Two Treatments for Children with Lennox-Gastaut Syndrome

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
Sandi Lam, MD, MBA
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Ways to Treat Children with Inactive Spondyloarthritis -- The BACK-OFF JSpA Study

Children's Hospital of Philadelphia
| Pennsylvania
Pamela Weiss, MD, AB
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Ways to Treat PTSD among Veterans

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Keith Bredemeier, PhD, BA
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Testing the Effectiveness of a Text-Message-Based Home Monitoring Program and Oxygen Monitoring for Patients with COVID-19 -- The COVID Watch Study

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Mucio Kit Delgado, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Ways to Treat Anxiety Disorders among Children and Adolescents

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
John T. Walkup, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Four Ways to Treat Opioid Use Disorder

Philadelphia College of Osteopathic Medicine
| Pennsylvania
Michelle Lent
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Ways to Promote Quitting Smoking for People Referred for Lung Cancer Screenings

University of Pennsylvania
| Pennsylvania
Scott Halpern, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Ways to Help Primary Care Providers Prescribe Opioids Safely

University of Pittsburgh
| Pennsylvania
Kevin Kraemer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Offer Palliative Care to Improve Quality of Life for Patients with End-Stage Liver Disease

Thomas Jefferson University
| Pennsylvania
Victor J. Navarro, MD, BS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Programs to Treat Opioid Use Disorder in Primary Care and Substance Use Clinics

Public Health Management Corporation^
| Pennsylvania
David R. Gastfriend, MD
Project Status:
Terminated
Project Type:
Research
Has Results

Comparing Mobile Stroke Unit Treatment with Emergency Room Care among Patients Who Have Had a Stroke -- The BEST-MSU Study

Memorial Hermann-Texas Medical Center
| Texas
James Grotta, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Medicines to Prevent Chronic Obstructive Pulmonary Disease Episodes -- The RELIANCE Study

University of Illinois at Chicago
| Illinois
Jerry A. Krishnan, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Types of Blood Thinners to Prevent Blood Clots in Patients with Cancer -- The CANVAS Trial

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Deborah Schrag, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Helping People with Opioid Use Disorders Avoid Relapses after Leaving Jail

University of Pennsylvania
| Pennsylvania
George Woody, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Types of Anesthesia for Hip Fracture Surgery -- The REGAIN Trial

University of Pennsylvania
| Pennsylvania
Mark D. Neuman, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Graphic Novels when Choosing Treatment for Alcohol Use Disorder

Public Health Management Corporation^
| Pennsylvania
Adam Brooks, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Broad- and Narrow-Spectrum Antibiotics for Children with Ear, Sinus, and Throat Infections

The Children's Hospital of Philadelphia
| Pennsylvania
Jeffrey Gerber, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Anti-TNF Drugs versus Long-Term Steroid Use for Patients with Inflammatory Bowel Diseases

University of Pennsylvania
| Pennsylvania
James Lewis, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does Plasma Exchange Help Improve Physical Function in Children with Transverse Myelitis? -- The CAPTURE Study

University of Texas Southwestern Medical Center
| Texas
Benjamin M. Greenberg, MD, MHS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

For Children Discharged after Hospitalization for Serious Bacterial Infections, Are Orally Administered Antibiotics as Effective as Antibiotics Given Intravenously through a PICC?

The Children's Hospital of Philadelphia
| Pennsylvania
Ron Keren, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Nonsurgical Treatments for Lumbar Spinal Stenosis in Reducing Pain and Increasing Walking Ability

University of Pittsburgh
| Pennsylvania
Michael J. Schneider, DC, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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