Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 28 results

Project Title
Project Status
Project Type

My Anesthesia Choice: Implementing an Evidence-Based Approach to Increase Shared Decision Making

University of Pennsylvania
| Pennsylvania
Mark Neuman, M.D., M.S.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

The Emotion Awareness and Skills Enhancement (EASE) Program versus the Unified Protocol (UP)

University of Pittsburgh
| Pennsylvania
Carla Mazefsky, Ph.D.
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Pacing Treatments for Patients with Heart Failure

Baylor College of Medicine
| Texas
Mihail G. Chelu, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparative Effectiveness of Brief Strength and Balance Exercises and Standard Home-Based Group Exercise for Primary Care Patients with Mobility Disability

Pennsylvania State University Hershey Medical Center
| Pennsylvania
Christopher Sciamanna, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Mild Hypoxic Ischemic Encephalopathy in Infants -- The COOLPRIME Study

UT Southwestern Medical Center
| Texas
Lina Chalak, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Developing Methods for Analyzing Clustered Observational Data When Death is a Semi-Competing Risk

The University of Texas Southwestern Medical Center
| Texas
Hong Zhu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Improving Instrumental Variables Methods for Non-Randomized Studies

The Trustees of The University of Pennsylvania
| Pennsylvania
Luke Keele, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Helping Researchers Assess How Well Data Reflect Clinical Context

Children's Hospital of Philadelphia
| Pennsylvania
Charles Bailey, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Expanding the Use of Reports That Capture Age-Related Problems to Improve Doctor-Patient Conversations in Community Cancer Clinics

The University of Texas MD Anderson Cancer Center
| Texas
Lisa Lowenstein, PhD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing Two Ways to Prevent Suicide among Alaska Native Young People -- The BeWeL Study

RAND Corporation
| Pennsylvania
Elizabeth D'Amico, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Manage Lymphedema among Head and Neck Cancer Survivors

The Trustees of The University of Pennsylvania
| Pennsylvania
Jie Deng, PhD, MSN, RN
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Improve Heart Health for Black Birthing People

Temple University
| Pennsylvania
Sharon Herring, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Monitor and Treat High Blood Pressure in Children with Chronic Kidney Disease -- The PRESERVE Study

Children's Hospital of Philadelphia
| Pennsylvania
Christopher Forrest, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Developing Methods to Help Identify Patients with Rare Diseases in Electronic Health Records

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Daniel Herman, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Ways to Treat Children with Inactive Spondyloarthritis -- The BACK-OFF JSpA Study

Children's Hospital of Philadelphia
| Pennsylvania
Pamela Weiss, MD, AB
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Developing Methods to Analyze Data Missing Due to Death in Cluster Randomized Trials

Trustees of the University of Pennsylvania
| Pennsylvania
Michael Harhay, PhD, MPH, MA, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Three Ways to Treat PTSD among Veterans

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Keith Bredemeier, PhD, BA
Project Status:
In progress; Recruiting
Project Type:
Research

Implementing Best-Practice, Patient-Centered Venous Thromboembolism (VTE) Prevention in Trauma Centers

Coalition for National Trauma Research
| Texas
Elliott Haut, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing Ways to Monitor Patients with Multiple Chronic Conditions after They Return Home from the Hospital for an Infection -- The ACCOMPLISH Study

UPMC Center for High ValueHealth Care
| Pennsylvania
Dr. Kalpana Char, MD*
Project Status:
In progress; Recruiting
Project Type:
Research

Improving Antibiotic Prescribing in Children with Ear, Sinus, and Throat Infections

The Children's Hospital of Philadelphia
| Pennsylvania
Jeffrey Gerber, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Comparing Four Ways to Treat Opioid Use Disorder

Philadelphia College of Osteopathic Medicine
| Pennsylvania
Michelle Lent
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Offer Behavioral Therapy for Children with ADHD from Families with Low Incomes -- The PASS Study

Children's Hospital of Philadelphia
| Pennsylvania
Thomas Power, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Ways to Promote Quitting Smoking for People Referred for Lung Cancer Screenings

University of Pennsylvania
| Pennsylvania
Scott Halpern, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Programs to Treat Patients with Inflammatory Bowel Disease and Behavioral Health Conditions

UPMC Center for High ValueHealth Care
| Pennsylvania
Eva Szigethy, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Offer Palliative Care to Improve Quality of Life for Patients with End-Stage Liver Disease

Thomas Jefferson University
| Pennsylvania
Victor J. Navarro, MD, BS
Project Status:
In progress; Recruiting
Project Type:
Research

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