Explore Our Portfolio
Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio |
Displaying 1 - 15 of 15 results
Project Title
Project Status
Project Type
Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain
RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Comparing Cognitive Behavioral Therapy with Peer-Led Support Groups for Patients with Chronic Pain Who Want to Reduce Opioid Use -- The EMPOWER Study
Stanford University School of Medicine
| California
Beth Darnall, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results
Comparing a Multiple Sclerosis Fatigue Management Course Delivered via Teleconference, Internet, or in Person
Case Western Reserve University
| Ohio
Matthew A. Plow, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Comparing Home and Facility-Based Exercise to Improve Mobility in People with Multiple Sclerosis -- STEP for MS
Shepherd Center
| Georgia
Deborah A. Backus, PhD, PT
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Examining Whether Early Aggressive Therapy Can Prevent or Delay Disability in People with Multiple Sclerosis: the TREAT-MS Study
Johns Hopkins University
| Maryland
Ellen M. Mowry, MD, MCR
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Comparing the Effectiveness of Three Treatments for Reducing Fatigue among Patients with Multiple Sclerosis -- The COMBO-MS Trial
University of Michigan
| Michigan
Tiffany J. Braley, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Comparing Two Approaches to Treat Relapsing-Remitting Multiple Sclerosis -- the DELIVER-MS Study
Cleveland Clinic Foundation
| Ohio
Daniel Ontaneda, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results
Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study
Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results
Comparing Treatment Approaches for Older Adults with Treatment-Resistant Depression -- The OPTIMUM Study
Washington University School of Medicine
| Missouri
Eric J. Lenze, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results
Comparing ECT and Ketamine in Adults with Treatment-Resistant Depression – The ELEKT-D Study
Cleveland Clinic Foundation
| Ohio
Amit Anand, MD^
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results
Comparing Ways to Help Veterans Manage Chronic Pain -- The VOICE Study
University of Minnesota Twin Cities
| Minnesota
Erin Krebs, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Comparing Two Oral Medicines to Improve Patient Experiences with Relapsing-Remitting Multiple Sclerosis -- PRAG-MS
Fondazione IRCCS Istituto Neurologico "Carlo Besta" (Italy)
| N/A
Renato Mantegazza, MD^
Project Status:
Terminated
Project Type:
Research
Comparing Clinic- and Home-Based Exercise Programs to Help Adults with Multiple Sclerosis -- The TEAMS Study
University of Alabama at Birmingham
| Alabama
James Rimmer, PhD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results
Comparing the Safety and Effectiveness of Different Medicines to Treat Multiple Sclerosis -- The COMBAT-MS Study
Karolinska Institute (Sweden)
| N/A
Fredrik Piehl, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results
Comparing Medicines to Help Patients with Multiple Sclerosis Feel Less Fatigued -- The TRIUMPHANT-MS Study
Johns Hopkins University^
| Maryland
Bardia Nourbakhsh, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research