Explore Our Portfolio
Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio |
Displaying 1 - 17 of 17 results
Project Title
Project Status
Project Type
Has Results
Comparing Two Medicines to Prevent Blood Clots after Treatment for Fractures -- The PREVENT CLOT Study
University of Maryland Baltimore
| Maryland
Robert V. O'Toole, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study
Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results
Comparing Treatment Approaches for Older Adults with Treatment-Resistant Depression -- The OPTIMUM Study
Washington University School of Medicine
| Missouri
Eric J. Lenze, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results
Comparing ECT and Ketamine in Adults with Treatment-Resistant Depression – The ELEKT-D Study
Cleveland Clinic Foundation
| Ohio
Amit Anand, MD^
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Comparing Two Oral Medicines to Improve Patient Experiences with Relapsing-Remitting Multiple Sclerosis -- PRAG-MS
Fondazione IRCCS Istituto Neurologico "Carlo Besta" (Italy)
| N/A
Renato Mantegazza, MD^
Project Status:
Terminated
Project Type:
Research
Has Results
Comparing the Safety and Effectiveness of Different Medicines to Treat Multiple Sclerosis -- The COMBAT-MS Study
Karolinska Institute (Sweden)
| N/A
Fredrik Piehl, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results
Comparing Medicines to Help Patients with Multiple Sclerosis Feel Less Fatigued -- The TRIUMPHANT-MS Study
Johns Hopkins University^
| Maryland
Bardia Nourbakhsh, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing Two Ways to Manage Symptoms for Patients Who Have Chronic Migraine and Frequent Medication Use -- The MOTS Trial
Mayo Clinic Arizona
| Arizona
Todd J. Schwedt, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Comparing Two Medicines to Prevent Chronic Obstructive Pulmonary Disease Episodes -- The RELIANCE Study
University of Illinois at Chicago
| Illinois
Jerry A. Krishnan, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Comparing Ways to Decrease Severe Asthma Attacks among Black and Latinx Adults with Moderate to Severe Asthma -- The PREPARE Study
Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Elliot Israel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Comparing Treatment Options for Women with Low-Risk Ductal Carcinoma In Situ (DCIS) -- The COMET Study
Alliance for Clinical Trials in Oncology Foundation
| Illinois
Shelley Hwang, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research
Comparing Medicines to Prevent Blood Clots in Patients Who Have Hip or Knee Replacement Surgery -- The PEPPER Study
Dartmouth-Hitchcock Clinic^
| New Hampshire
Vincent Domenic Pellegrini, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results
Comparing Antibiotics versus Surgery for Treating Appendicitis -- The CODA Study
University of Washington
| Washington
David Reed Flum, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing Ways to Manage Weight and Overall Health in Overweight and Obese Youth with Bipolar Spectrum Disorders Who Take Antipsychotic Medicines -- The MOBILITY Study
University of Cincinnati
| Ohio
Melissa P. DelBello, MD, MS
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research
Has Results
Comparing Two Types of Anesthesia for Hip Fracture Surgery -- The REGAIN Trial
University of Pennsylvania
| Pennsylvania
Mark D. Neuman, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing the Safety and Effectiveness of Medicines to Treat Crohn’s Disease in Children and Adolescents -- The COMBINE Trial
The University of North Carolina at Chapel Hill
| North Carolina
Michael D. Kappelman, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Comparing Ways to Improve Prescribing of Colony-Stimulating Factor in Cancer Treatment -- The TrACER Study
Fred Hutchinson Cancer Research Center
| Washington
Scott D. Ramsey, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research