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State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 14 of 14 results

Project Title
Project Status
Project Type

Comparing Two Treatment Options for Recurrent Bladder Cancer

University of Washington Office of Sponsored Programs, Department of Urology
| Washington
John Gore, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Using Two Versus Three Antibiotics to Treat MAC Lung Infections

Oregon Health & Science University
| Oregon
Kevin Winthrop, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Two Medicines to Prevent Blood Clots after Treatment for Fractures -- The PREVENT CLOT Study

University of Maryland Baltimore
| Maryland
Robert V. O'Toole, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Oral Medicines to Improve Patient Experiences with Relapsing-Remitting Multiple Sclerosis -- PRAG-MS

Fondazione IRCCS Istituto Neurologico "Carlo Besta" (Italy)
Renato Mantegazza, MD^
Project Status:
Terminated
Project Type:
Research
Has Results

Comparing Safety and Effectiveness of Medicines Patients Take for Many Years to Treat Multiple Sclerosis (MS) -- The COMBAT-MS Study

Karolinska Institute (Sweden)
Fredrik Piehl, MD, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Medicines to Help Patients with Multiple Sclerosis Feel Less Fatigued -- The TRIUMPHANT-MS Study

Johns Hopkins University^
| Maryland
Bardia Nourbakhsh, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Manage Symptoms for Patients Who Have Chronic Migraine and Frequent Medication Use -- The MOTS Trial

Mayo Clinic Arizona
| Arizona
Todd J. Schwedt, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Medicines to Prevent Chronic Obstructive Pulmonary Disease Episodes -- The RELIANCE Study

University of Illinois at Chicago
| Illinois
Jerry A. Krishnan, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Treatment Options for Women with Low-Risk Ductal Carcinoma In Situ (DCIS) -- The COMET Study

The Alliance for Clinical Trials In Oncology Foundation
| Illinois
Shelley Hwang, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Medicines to Prevent Blood Clots in Patients Who Have Hip or Knee Replacement Surgery -- The PEPPER Study

Dartmouth-Hitchcock Clinic^
| New Hampshire
Vincent Domenic Pellegrini, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Antibiotics versus Surgery for Treating Appendicitis -- The CODA Study

University of Washington
| Washington
David Reed Flum, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Ways to Manage Weight and Overall Health in Overweight and Obese Youth with Bipolar Spectrum Disorders Who Take Antipsychotic Medicines -- The MOBILITY Study

University of Cincinnati
| Ohio
Melissa P. DelBello, MD, MS
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing How Two Types of Anesthesia Affect Recovery from Hip Fracture Surgery -- The REGAIN Trial

University of Pennsylvania
| Pennsylvania
Mark D. Neuman, MD, MS
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Treatments for Children with Crohn's Disease -- The COMBINE Trial

The University of North Carolina at Chapel Hill
| North Carolina
Michael Kappelman, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

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