Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 24 of 24 results

Project Title
Project Status
Project Type

Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement

University of Pennsylvania
| Pennsylvania
Mucio Delgado, MD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Help Patients Control High Blood Pressure

Brody School of Medicine at East Carolina University
| North Carolina
Doyle Cummings, PharmD
Project Status:
In progress; Recruiting
Project Type:
Research

Does Treating Genital Herpes in Pregnancy Reduce Racial Disparities in Severe Maternal Morbidity? -- The PCORI SMM Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
De-Kun Li, MD, MPH, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Offer Remote Therapy for Depressive Symptoms in People with Heart Disease

University of Kentucky
| Kentucky
Debra Moser, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Prevent Severe Hypoglycemia in Patients with Type 2 Diabetes

Kaiser Foundation Health Plan of Washington
| Washington
James Ralston, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Provide Follow-Up Care to Patients with Heart Failure after Hospital Discharge -- MIGHTY-Heart

The Trustees of Columbia University in the City of New York
| New York
Ruth Masterson Creber, PhD^
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Improve Pre-Exposure Prophylaxis (PrEP) Use for HIV Prevention

Public Health Foundation Enterprises, Inc.
| California
Albert Liu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Start Taking Medicine for Opioid Use Disorder

University of Colorado Anschutz Medical Campus
| Colorado
Linda Zittleman, MPH, MS
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Self-Management in Older Adults with Chronic Heart Failure -- The iCOACH Study

University of Arkansas for Medical Sciences
| Arkansas
Judy Weber, PhD, RD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Stroke and Blood Clot Risk in Transgender Women Taking Hormones

Emory University
| Georgia
Michael Goodman, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Treatments for Dental Cavities in Older Adults Living in Low-Income Housing

Case Western Reserve University
| Ohio
Suchitra Nelson, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Coordinate Care for Patients after Trauma

University of Washington
| Washington
Douglas Zatzick, MD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain

RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Cognitive Behavioral Therapy with Peer-Led Support Groups for Patients with Chronic Pain Who Want to Reduce Opioid Use -- The EMPOWER Study

Stanford University School of Medicine
| California
Beth Darnall, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Mobile Stroke Unit Treatment with Emergency Room Care among Patients Who Have Had a Stroke -- The BEST-MSU Study

Memorial Hermann-Texas Medical Center
| Texas
James Grotta, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Help Veterans Manage Chronic Pain -- The VOICE Study

University of Minnesota Twin Cities
| Minnesota
Erin Krebs, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Examining Whether a Self-Care Program Reduces Healthcare Use and Improves Health among Patients with Acute Heart Failure -- The GUIDED HF Study

Vanderbilt University Medical Center
| Tennessee
Sean P. Collins, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Help African Americans Who Are Non-Daily Smokers Quit Smoking

University of Kansas Medical Center Research Institute, Inc.
| Kansas
Nikki Nollen, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Evaluating a Program to Lower Prescription Opioid Doses for Patients with Chronic Pain

Kaiser Foundation Health Plan of Washington^
| Washington
Michael Von Korff, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Smartphone App Help Patients with Cancer Take Oral Chemotherapy as Planned?

Massachusetts General Hospital
| Massachusetts
Joseph A. Greer, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Examining Health Outcomes for People Who Are Transgender

Emory University
| Georgia
Michael Goodman, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Do People with Obesity Lose Weight When Offered a Choice of Research-Based Weight-Loss Treatment by Their Doctors?

Denver Health and Hospital Authority
| Colorado
Daniel Bessesen, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Do Education, Case Management, and Advanced Practice Pharmacy Services Improve Health among American Indian and Alaska Native Peoples with Diabetes?

University of Colorado Denver
| Colorado
Joan O'Connell, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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