Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 43 results

Project Title
Project Status
Project Type

Comparing Two Pacing Treatments for Patients with Heart Failure

Baylor College of Medicine
| Texas
Mihail G. Chelu, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Online Programs for Treating Chronic Pain -- The PROGRESS Study

Stanford University
| California
Beth Darnall, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Prevention Programs for Teens at Risk for Suicide

Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Improve Mental Health among Youth with Disabilities -- The BEST Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat Anxiety in Patients Who Go to the Emergency Room with Low-Risk Chest Pain

Trustees of Indiana University
| Indiana
Paul Musey, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Self-Management in Older Adults with Chronic Heart Failure -- The iCOACH Study

University of Arkansas for Medical Sciences
| Arkansas
Judy Weber, PhD, RD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Three Ways to Treat Insomnia in Adults Living in Rural Areas

Sutter Bay Hospital
| California
Katie Stone, PhD, MA
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Help Sexual and Gender Minority Men Who Have Been Sexually Abused Reduce Depression and Increase Mental Health Treatment Engagement

Yale University
| Connecticut
Joan M. Cook, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Remote Cognitive Behavior Therapy for Major Depression in Primary Care

University of South Florida
| Florida
Robert Bossarte, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Treatment Options for Recurrent Bladder Cancer

University of Washington Office of Sponsored Programs, Department of Urology
| Washington
John Gore, MD, MS
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Two Programs to Treat Patients with Inflammatory Bowel Disease and Behavioral Health Conditions

UPMC Center for High ValueHealth Care
| Pennsylvania
Eva Szigethy, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Two Programs to Reduce Unsafe Opioid Prescribing and Improve Outcomes among People Who Are Injured at Work -- The WOW Study

University of Washington
| Washington
Gary Franklin, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Ways to Coordinate Care for Patients after Trauma

University of Washington
| Washington
Douglas Zatzick, MD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Two Ways to Treat Youth with Anxiety or Obsessive-Compulsive Disorder (OCD)

Emma Pendleton Bradley Hospital
| Rhode Island
Jennifer Freeman, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain

RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Cognitive Behavioral Therapy with Peer-Led Support Groups for Patients with Chronic Pain Who Want to Reduce Opioid Use -- The EMPOWER Study

Stanford University School of Medicine
| California
Beth Darnall, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing the Effectiveness of Three Treatments for Reducing Fatigue among Patients with Multiple Sclerosis -- The COMBO-MS Trial

University of Michigan
| Michigan
Tiffany J. Braley, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Testing One State's Effort to Prevent Unsafe Treatments for Patients with Back Pain -- Back on Track

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| Washington
Lynn DeBar, PhD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Ways to Provide Palliative Care for Patients with Advanced Lung Cancer

Massachusetts General Hospital
| Massachusetts
Jennifer S. Temel, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Offer Palliative Care to Improve Quality of Life for Patients with End-Stage Liver Disease

Thomas Jefferson University
| Pennsylvania
Victor J. Navarro, MD, BS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Encourage and Improve End-of-Life Care Planning

Duke University
| North Carolina
Kimberly Johnson, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Managing Long-Term Low Back Pain to Improve Health and Reduce Reliance on Opioid Medicines: Comparing Mindfulness Meditation and Cognitive Behavioral Therapy -- Strategies To Assist with Management of Pain (STAMP)

University of Wisconsin-Madison
| Wisconsin
Bruce Barrett
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Help Veterans Manage Chronic Pain -- The VOICE Study

University of Minnesota Twin Cities
| Minnesota
Erin Krebs, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Three Approaches to Improve Diabetes Self-Care among African-American Adults -- The MODEL Study

The University of Tennessee Health Science Center
| Tennessee
James E. Bailey, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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