Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 94 results

Project Title
Project Status
Project Type

Impact of Doula Support During Pregnancy, Childbirth and Beyond (A Health Equity Systematic Review)

RTI International
| North Carolina
Meera Viswanathan, PhD
Project Status:
Ongoing
Project Type:
Research

Hospital-to-Home Care Coordination for Children and Youth With Special Healthcare Needs

Duke University
| North Carolina
David Ming, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

Thriving Hearts: Healing-Centered, Integrated, Community Maternity Care

The University of North Carolina at Chapel Hill
| North Carolina
Alison Stuebe, B.S., M.D., MSc
Project Status:
Awarded; Contract pending
Project Type:
Research, Research Conducted Using PCORnet®

Implementation and Interaction of Clinician and Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure With Reduced Ejection Fraction

University of Colorado Denver
| Colorado
Larry Allen, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Remote Hypertension Tracking Help and Management to Reduce Disparities in Black Patients (RHYTHM-B)

Wake Forest University Health Sciences
| North Carolina
Yhenneko Taylor, Ph.D., Mstat
Project Status:
Awarded; Contract pending
Project Type:
Research

Reducing Future Fractures and Improving Outcomes of Fragility Fracture -- The RESTORE Study

The University of Alabama at Birmingham
| Alabama
Kenneth Saag, M.D., M.Sc.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Models of Post-Acute Care in Complex Older Adults with Fracture

Duke University School of Medicine
| North Carolina
Cathleen Colon-Emeric, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Enhanced Primary Telecare versus Consultative Complex Care for Children with Medical Complexity

Wake Forest School of Medicine
| North Carolina
Savithri Nageswaran, M.D., MPH, MBBS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Trial of Sequential Medications AfteR TNF failure in Juvenile Idiopathic Arthritis (SMART-JIA)

Duke University
| North Carolina
Laura Schanberg, M.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Measuring Co-Creation During the Engagement Process in Research: A Pathway Forward

University of Colorado Denver
| Colorado
Monica Perez Jolles, Ph.D., M.A.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Reduce Overuse of Antibiotics among Children with Ear Infections -- The DIsAPEAR Study

Denver Health and Hospital Authority
| Colorado
Holly Frost, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Cognitive-Behavioral Therapy versus Mindfulness-Based Therapy for Autistic Adults

The University of North Carolina at Chapel Hill
| North Carolina
Brenna Maddox, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

A Comparison of Two School-Based Interventions to Manage Anxiety in Autistic Students

University of Colorado Denver
| Colorado
Judy Reaven, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Develop Novel Methods to Identify and Characterize Family Relationships from Electronic Health Data

University of Colorado Denver
| Colorado
Toan Ong, PhD, and Lisa Schilling, MD, MSPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparative Effectiveness of an Individualized Model of Hemodialysis versus Conventional Hemodialysis

Wake Forest University
| North Carolina
Mariana Murea, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Help Patients Control High Blood Pressure

Brody School of Medicine at East Carolina University
| North Carolina
Doyle Cummings, PharmD
Project Status:
In progress; Recruiting
Project Type:
Research

Audio Care for the Management of Mental Health and Chronic Conditions (Systematic Reviews)

RTI International
| North Carolina
Sheila Patel, PhD
Project Status:
Ongoing
Project Type:
Research

Comparing Two Ways to Monitor Symptoms from Dialysis -- The SMaRRT-HD Trial

The University of North Carolina at Chapel Hill
| North Carolina
Jennifer Flythe, MD, MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways for Parents of Youth with Intellectual and Developmental Disabilities to Build Their Advocacy Skills

The University of North Carolina at Chapel Hill
| North Carolina
Kathleen Thomas, MPH, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Prevent Suicide among Autistic Youth

The University of North Carolina at Chapel Hill
| North Carolina
Brenna Maddox, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Control Blood Pressure after Stroke

Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Four Ways to Reduce Pregnancy Complications among Black Mothers -- The ACURE4Moms Study

University of North Carolina at Chapel Hill School of Medicine
| North Carolina
Jennifer Tang, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Testing Two Ways to Increase Receipt of Early Kidney Transplants among Patients with Kidney Failure

Duke University
| North Carolina
Leigh Ebony Boulware, MD, MPH, FACP
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Patients with Rheumatoid Arthritis -- The RA-PRO PRagmatic Trial (RA-PROPR)

The University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

The HERO Research Program -- A PCORnet® Project to Support Studies on COVID-19

Duke University
| North Carolina
Adrian Hernandez, MD, MHS; Emily O'Brien, PhD (HERO registry); Susanna Naggie, MD (HERO-HCQ trial)
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

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