Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 34 results

Project Title
Project Status
Project Type
Has Results

Comparing the Safety and Effectiveness of Metformin with Other Medicines for Patients with Type 2 Diabetes and Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
James Flory, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Identifying Barriers to Telehealth Home-Based Palliative Care for Patients with Serious Illness -- The HomePal Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Huong Q. Nguyen, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Three Ways to Help Patients with Acute Pain Learn about Opioid Risks -- The Life STORRIED Study

University of Pennsylvania
| Pennsylvania
Zachary F. Meisel, MD, MPH, MSHP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Benefits and Harms of Different Long-Term Treatments for Blood Clots -- The DARE Warfarin Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Katsiaryna Bykov, PharmD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment Strategies to Prevent Future Blood Clots among Patients Who Received at Least Three Months of Blood Thinners -- The ALTERNATIVE Study

University of California, San Francisco
| California
Margaret Fang, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Approaches to Improve Diabetes Self-Care among African-American Adults -- The MODEL Study

The University of Tennessee Health Science Center
| Tennessee
James E. Bailey, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment Options for Urea Cycle Disorders

Children's Research Institute
| District of Columbia
Nicholas Ah Mew, MD^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Oral Medicines to Treat Hepatitis C Virus -- The PRIORITIZE Study

University of Florida
| Florida
David Robert Nelson, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Reduce High Blood Pressure in Patients from Different Racial and Ethnic Groups -- The RICH LIFE Study

Johns Hopkins University
| Maryland
Lisa A. Cooper, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Helping People with Opioid Use Disorders Avoid Relapses after Leaving Jail

University of Pennsylvania
| Pennsylvania
George Woody, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Changes in Health for Patients Who Complete Treatment for Chronic Hepatitis C Virus -- The PROP up TARGET Study

The University of North Carolina at Chapel Hill
| North Carolina
Donna Evon, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Program to Help Patients Prepare for Kidney Failure Treatment -- The PREPARE NOW Study

Duke University
| North Carolina
Leigh E. Boulware, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods for Comparing Treatments Using Different Ways of Grouping Patients

University of California, San Francisco^
| California
Mi-Ok Kim, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Designing and Testing a Visit Planner to Help Patients Address Their Top Concerns during Healthcare Visits

Kaiser Foundation Research Institute
| California
Richard W. Grant, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Help Latinx Patients with Depression Who Are Age 50 or Older

University of Southern California
| California
Maria P. Aranda, PhD, MPA, MSW
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Program to Help Monitor Chronic Hepatitis B among Asian-American Patients

Temple University
| Pennsylvania
Grace X. Ma, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Self-Management of Urinary Symptoms Using a Probiotic in People with Spinal Cord Injuries, Spina Bifida, and Multiple Sclerosis

MedStar Health Research Institute
| Maryland
Suzanne Groah, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Treatments for Depression among Patients with Kidney Failure Receiving Hemodialysis -- The ASCEND Study

University of Washington
| Washington
Rajnish Mehrotra, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Improve Quality of Life for Patients with Kidney Disease and Their Caregivers

Pennsylvania State University Hershey Medical Center
| Pennsylvania
Nasrollah Ghahramani, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Increase Hepatitis B and C Screening among Asian Americans

University of California, San Francisco
| California
Tung Nguyen, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing Software for Using Bayesian Regression to Evaluate Heterogeneity of Treatment Effects in Data from Randomized Controlled Trials

Johns Hopkins University
| Maryland
Ravi Varadhan, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Effect of End-of-Life Care Planning Discussions on Hospice Use among Patients Receiving Dialysis for Kidney Failure

Baystate Medical Center
| Massachusetts
Lewis Mitchel Cohen, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Evaluating a Patient-Centered Medical Home for Patients Receiving Dialysis for Kidney Disease

University of Illinois at Chicago
| Illinois
Denise Hynes, MPH, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Improving Communication by Preparing Patients and Doctors for a Conversation about Care Goals for Serious Illness

University of Washington
| Washington
J. Randall Curtis, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Five Activities to Improve Quality of Life for Patients with Mild Cognitive Impairment

University of Florida^
| Florida
Glenn E. Smith, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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