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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year the PCORI Board of Governors approved funding for the project or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 34 results

Project Title
Project Status
Project Type

Natural Experiments Coordinating Center

Regents of the University of California, Los Angeles
| California
Kenrik Duru, MD, MSHS
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure

Dissemination and Implementation of Causal Inference Methods through Partnerships with Large Health Systems

Medical Technology and Practice Patterns Institute
| Maryland
Yi Zhang, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing Three Approaches to Improve Communication Between Patients and Their Doctors

University of California, San Diego^
| California
Ming Tai-Seale, PhD, MPA
Project Status:
In progress; Recruiting
Project Type:
Research

Does Type of Insurance Plan Affect Asthma Control in Adults and Children? -- AFFORD

Harvard Pilgrim Health Care, Inc.
| Massachusetts
Alison Amidei Galbraith, MD, MPH
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Can Early Tracheostomy Improve Recovery and Survival in Patients with Severe Stroke and Breathing Failure? -- The SETPOINT 2 Study

Maine Medical Center
| Maine
David Seder, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Three Medicines to Prevent Blood Clots in Patients Who Need Long-Term Blood-Thinning Treatment -- The COVET Trial

Duke University
| North Carolina
Thomas L. Ortel, MD, PhD
Project Status:
Terminated
Project Type:
Research
Has Results

Comparing Mobile Stroke Treatment with Emergency Room Care -- the BEST-MSU Study

Memorial Hermann Health System, Memorial Hermann-Texas Medical Center
| Texas
James Grotta, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Does Reporting Symptoms Between Doctor Visits Improve Length and Quality of Life in Patients with Advanced Cancer? -- The PRO-TECT Trial

The Alliance for Clinical Trials In Oncology Foundation
| Illinois
Ethan Basch, MD, MSc
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Follow-Up Care to Patients after Bone Marrow Transplants

Dana-Farber Cancer Institute
| Massachusetts
Gregory Abel, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Engaging Patients and Providers in Collaborative Communication on HPV Vaccination (EPPIC-HPV)

University of New Mexico Main Campus
| New Mexico
Gill Woodall, PhD
Project Status:
Terminated
Project Type:
Research

Providing at-Home Kidney Disease Care for Native Americans in New Mexico

University of New Mexico Health Sciences Center
| New Mexico
Vallabh O. Shah, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Medicines that Prevent Blood Clots for Emergency Room Patients with Serious Fractures -- The PREVENT CLOT Study

University of Maryland Baltimore
| Maryland
Robert O'Toole, MD, TRD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing the Benefits and Harms of Five Different Medicines for Long-Term Treatment of Blood Clots -- The DARE Warfarin Study

Brigham and Women's Hospital
| Massachusetts
Katsiaryna Bykov, PharmD, ScD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Treatments for Older Adults Who Have Major Depression That Does Not Respond to First-Line Antidepressant Medicines -- The OPTIMUM Study

Washington University School of Medicine
| Missouri
Eric Juckeland Lenze, MD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing ECT and Ketamine in Adults with Treatment-Resistant Depression – The ELEKT-D Study

Cleveland Clinic Foundation
| Ohio
Amit Anand, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Managing Long-Term Low Back Pain to Improve Health and Reduce Reliance on Opioid Medicines: Comparing Mindfulness Meditation and Cognitive Behavioral Therapy -- Strategies To Assist with Management of Pain (STAMP)

University of Wisconsin-Madison
| Wisconsin
Bruce Barrett
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Help Veterans Manage Pain and Reduce Use of Prescription Opioid Medicines -- The VOICE Study

University of Minnesota Twin Cities
| Minnesota
Erin Krebs, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Oral Medicines to Improve Patient Experiences with Relapsing-Remitting Multiple Sclerosis -- PRAG-MS

Fondazione IRCCS Istituto Neurologico "Carlo Besta" (Italy)
Renato Mantegazza, MD^
Project Status:
Terminated
Project Type:
Research

Comparing Clinic- and Home-Based Exercise Programs to Help Adults with Multiple Sclerosis -- The TEAMS Study

University of Alabama at Birmingham
| Alabama
James Rimmer, PhD, MA
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Safety and Effectiveness of Medicines Patients Take for Many Years to Treat Multiple Sclerosis (MS) -- The COMBAT-MS Study

Karolinska Institute (Sweden)
Fredrik Piehl, MD, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Project Data Link - Humana

Humana- Comprehensive Health Insights
| Kentucky
Vinit Nair, BPhar, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
PCORnet Initiative on Health Plan/System Data Partnerships (A Stepwise Approach to Collaboration)

HealthCore-Anthem Research Network (HCARN)

Health Core, Inc.
| Delaware
Kevin Haynes, MS, PhrmD
Project Status:
Awarded; In progress
Project Type:
PCORnet Initiative on Health Plan/System Data Partnerships (A Stepwise Approach to Collaboration)

The Role of Breast Density in Decision Making for Breast Cancer Screening and Diagnostic Testing -- The BCSC-ADVANCE Study

University of California, Davis
| California
Diana Miglioretti, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Ways to Provide Hepatitis C Treatment for People Who Take Methadone

The Research Foundation for the State University of New York
| New York
Andrew Talal, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

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