Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 65 results

Project Title
Project Status
Project Type

Promoting Shared Decision Making for Decisions about Treatment of Severe Aortic Stenosis

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

PEDSnet: Advancing Pediatric Patient-Centered Outcomes Research in PCORnet

The Children's Hospital of Philadelphia
| Pennsylvania
Christopher Forrest, MD, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

INSIGHT Clinical Research Network

Weill Cornell Medicine
| New York
Rainu Kaushal, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

OneFlorida+ Partner Engagement Network

University of Florida
| Florida
Elizabeth Shenkman, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

Accelerating Data Value Across a National Community Health Center Network (ADVANCE) Clinical Research Network (CRN)

Oregon Community Health Information Network, Inc. (OCHIN)
| Oregon
Erika Cottrell, PhD, MPP
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

Greater Plains Collaborative Optimizing Infrastructure for Conducting Patient-Centered Outcomes Research: PCORnet, The National Patient-Centered Clinical Research Network: Phase 3

University of Missouri
| Missouri
Lemuel Waitman, PhD, MS, BS
Project Status:
Awarded; Contract pending
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

The Stakeholders, Technology and Researchers (STAR) Clinical Research Network: Phase 3

Vanderbilt University Medical Center
| Tennessee
Russell Rothman, MD, MPP
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

PaTH to Health: PCORnet Clinical Research Network

University of Pittsburgh School of Medicine
| Pennsylvania
Kathleen McTigue, MD, MPH, MS
Project Status:
Awarded; Contract pending
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

REACHnet 3.0: Optimizing Infrastructure for Conducting Patient-Centered Outcomes Research

Louisiana Public Health Institute
| Louisiana
Thomas Carton, PhD, MS, BS
Project Status:
Awarded; Contract pending
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

Comparing Three Ways to Improve COVID-19 Vaccination Rates at Long-Term Care Centers -- The ENSPIRE Study

Kaiser Foundation Health Plan of Washington (Kaiser Permanente Washington Health Research Institute)
| California
Clarissa Hsu, PhD, MA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Increase Confidence in COVID-19 Vaccines among Long-Term Care Workers -- The CONFIDENT Trial

Trustees of Dartmouth College
| New Hampshire
Glyn Elwyn, MD, PhD, MSc
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Two Ways to Reduce Medicine Use among Older Patients with Type 2 Diabetes

Kaiser Foundation Hospitals
| California
Richard W. Grant, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Does Personalized Risk Information Help Patients and Doctors Make Informed Decisions about Colorectal Cancer Screening?

Indiana University
| Indiana
Peter H. Schwartz, MD, PhD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Ways to Increase HPV Testing for Cervical Cancer Screening

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Chun Chao, PhD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Supporting Shared Decision Making between Clinicians and Older Adults about Colorectal Cancer Screening -- The PRIMED Study

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD, and Leigh Simmons, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Decision Aid Help Older Adults with Chronic Kidney Disease Choose Treatment? -- The DART Study

Trustees of Tufts College
| Massachusetts
Keren Ladin, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Community Health Worker and Mobile Health Programs to Help Young Adults with Sickle Cell Disease Transition to Using Adult Healthcare Services -- The COMETS Study

The Childrens' Hospital of Philadelphia
| Pennsylvania
Tanisha Belton, DrPh, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Transitional Care for Teens and Young Adults with Sickle Cell Disease with and without Peer Mentoring

Atrium Health
| North Carolina
Payal Desai
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Help Parents of Children with Sickle Cell Disease Decide on Treatment -- The ENGAGE HU Study

Cincinnati Children's Hospital Medical Center
| Ohio
Lori E. Crosby, PsyD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Messaging Systems to Increase Use of Online Programs That Help Smokers Quit -- Smoker-to-Smoker (S2S)

University of Massachusetts Medical School
| Massachusetts
Rajani Sadasivam, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Approaches to Help Patients and Doctors Talk about Chronic Pain Treatments -- Voices in Pain Care

Cedars-Sinai Medical Center
| California
Brennan Spiegel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Engaging Patients and Providers in Collaborative Communication on HPV Vaccination (EPPIC-HPV)

University of New Mexico Main Campus
| New Mexico
Gill Woodall, PhD
Project Status:
Terminated
Project Type:
Research
Has Results

Comparing Three Ways to Help Patients with Acute Pain Learn about Opioid Risks -- The Life STORRIED Study

University of Pennsylvania
| Pennsylvania
Zachary F. Meisel, MD, MPH, MSHP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Helping Women with Breast Cancer Choose between Surgical Treatment Options

Dartmouth College
| New Hampshire
Glyn Elwyn, MD, PhD, MSc^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Higher and Lower Intensity Parent-Clinician Communication Trainings to Reduce Antibiotic Misuse in Children

Children's Mercy Hospital
| Missouri
Kathy Goggin, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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