Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 65 results

Project Title
Project Status
Project Type

Improving Heterogeneous Effect Estimation by Integration of Experimental and Observational Studies

Vanderbilt University Medical Center
| Tennessee
Amir Asiaeetaheri, Ph.D.
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Implementation of Symptom Monitoring with Electronic Patient-Reported Outcomes (ePROs) During Cancer Treatment: The OncoPRO Initiative

The University of North Carolina at Chapel Hill
| North Carolina
Ethan Basch, M.D., MPhil, M.S.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

The Dose Trial: Dose Intensity for Behavioral Interventions for Childhood Obesity

Vanderbilt University Medical Center
| Tennessee
William Heerman, M.D., MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Pragmatic Trial Comparing the Effectiveness of Ketamine versus Etomidate for Intubation

Vanderbilt University Medical Center
| Tennessee
Matthew Semler, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Revascularization Choices Among Under-Represented Groups Evaluation (The RECHARGE Program)

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Mario Gaudino, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Annual Wellness Visits versus GRACE-augmented Annual Wellness Visits for Older Adults with High Needs

Massachusetts General Hospital
| Massachusetts
Christine Ritchie, M.D., MSPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Putting a Depression Screening and Treatment Program in Place for Patients on Dialysis

University of Washington
| Washington
Rajnish Mehrotra, M.D., M.S.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Supporting the Use of a Treatment Approach in Health Systems to Improve Outcomes for Adults with Moderate to Severe Asthma

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Elliot Israel, M.D.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Learning to Predict Disease Trajectories

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
Mei-Sing Ong, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Identification of Temporal Data Patterns Predictive of Adverse Outcomes in Patients with Diabetes

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, M.D., MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Reduce Overuse of Antibiotics among Children with Ear Infections -- The DIsAPEAR Study

Denver Health and Hospital Authority
| Colorado
Holly Frost, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Disseminating New Evidence to Prevent Blood Clots in Patients with Bone Fractures

University of Maryland Baltimore
| Maryland
Nathan O'Hara, PhD, MHA
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Preventing Suicidal Behavior with Diverse High-Risk Youth in Acute Care Settings

Johns Hopkins University
| Maryland
Holly Wilcox, PhD, MA
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Promoting Informed Decision Making When Choosing between Antibiotics or Surgery for Appendicitis -- The TRIAD (Treatment Individualized Appendicitis Decision Making) Implementation Program

University of Washington
| Washington
David Flum, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Using a Smartphone Program to Help Patients Manage Symptoms of Serious Mental Illness

University of Washington
| Washington
Dror Ben-Zeev, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Supporting Pain Management for Sickle Cell Disease Crisis at Infusion Centers

Johns Hopkins School of Medicine
| Maryland
Sophie Lanzkron, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Implementing Matching of Patients to Mental Healthcare Therapists’ Strengths

University of Massachusetts Amherst
| Massachusetts
Michael Constantino, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Putting an Online Weight Management Program in Place in Clinical and Community Settings

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Heather J. Baer, ScD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Helping Researchers Assess How Well Data Reflect Clinical Context

Children's Hospital of Philadelphia
| Pennsylvania
Charles Bailey, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Expanding the Use of Reports That Capture Age-Related Problems to Improve Doctor-Patient Conversations in Community Cancer Clinics

The University of Texas MD Anderson Cancer Center
| Texas
Lisa Lowenstein, PhD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing Two Ways to Control Blood Pressure after Stroke

Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Expanding the Use of an End-of-Life Care Planning Program for Patients with Kidney Disease

The George Washington University School of Nursing
| Virginia
Dale Lupu, PhD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Expanding Use of the Health-E You/Salud iTu Mobile App to Promote Birth Control Use among Teens

The Regents of the University of California, San Francisco
| California
Kathleen Tebb, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Uptake of a Self-Care Program for Patients with Acute Heart Failure After Discharge from the Emergency Department

Vanderbilt University Medical Center
| Tennessee
Sean P. Collins, MD, MSc
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

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