Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 29 results

Project Title
Project Status
Project Type

Sequential Multiple Assignment Randomized Trial for Bipolar Depression: SMART-BD

Massachusetts General Hospital
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Provide Palliative Care for Patients Who Are in the Hospital with Acute Myeloid Leukemia

Massachusetts General Hospital
| Massachusetts
Areej El-Jawahri, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat PTSD among Veterans

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Keith Bredemeier, PhD, BA
Project Status:
In progress; Recruiting
Project Type:
Research

Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparative Effectiveness of Single-Site and Scattered-Site Permanent Supportive Housing on Patient-Centered and COVID-19 Related Outcomes for People Experiencing Homelessness

University of Southern California
| California
Benjamin Henwood, PhD, MA, MSW
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Ways to Treat People with PTSD and Substance Use Disorder -- The COMPASS Study

Center for Veterans Research and Education
| Minnesota
Shannon M. Kehle-Forbes, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Primary Care Treatment Options for People with PTSD

University of Washington
| Washington
John Fortney, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two School Behavioral Health Programs to Improve Students' Academic Performance and Mental Health

University of South Carolina
| South Carolina
Mark Weist, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Two Programs for Managing Long-Term Health Problems for People with Lived Experience of Mental Illness

Dartmouth-Hitchcock Clinic
| New Hampshire
Sarah Pratt, PhD^
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Coordinate Care for Patients after Trauma

University of Washington
| Washington
Douglas Zatzick, MD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain

RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Ways to Help Patients Manage Multiple Chronic Conditions

UPMC Center for High ValueHealth Care
| Pennsylvania
Dan Swayze
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Medications Added to a Serotonin Reuptake Inhibitor to Treat Patients with PTSD

University of California San Francisco
| California
Beth Cohen, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Helping People with Serious Mental Illness Stop Smoking

Massachusetts General Hospital
| Massachusetts
Eden Evins, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Testing a Program That Provides Care for Urgent Health Problems at Home Instead of the Emergency Room

Massachusetts General Hospital
| Massachusetts
Lisa I. Iezzoni, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Telehealth Approaches for Treating Complex Psychiatric Disorders in Primary Care -- The SPIRIT Study

University of Washington
| Washington
John C. Fortney, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Examining Effects of State Policies to Monitor Mental Health Medicines for Children in Foster Care

Rutgers University–New Brunswick
| New Jersey
Stephen Crystal, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing a Smartphone Program with a Peer-Led Program to Help People with Serious Mental Illness Manage Their Symptoms

University of Washington^
| Washington
Dror Ben-Zeev, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Peer-Navigator Support for Latinx Patients with Serious Mental Illness

Illinois Institute of Technology
| Illinois
Patrick William Corrigan, PsyD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Reporting Care Experiences of People with Significant Physical Disability or Serious Mental Illness to Primary Care Clinics

Massachusetts General Hospital
| Massachusetts
Lisa I. Iezzoni, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does Shared Decision Making Improve Care at Community Mental Health Clinics?

Family Service Agency of San Francisco
| California
Joyce Chu, PhD^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Are Treatment Groups Led by Peers as Effective as Groups Led by Counselors for Treating Posttraumatic Stress Disorder and Substance Use Disorder?

University of New Mexico Health Sciences Center
| New Mexico
Annette Crisanti, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Helping Patients with Mental Illness Engage in Their Transitional Care

University of Texas Health Science Center at San Antonio
| Texas
Dawn I. Velligan, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Peer-Led Program with Wellness Coaching Improve Wellness among People with Serious Mental Illness?

Yale University
| Connecticut
Chyrell Bellamy, PhD, MSW
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Web-Based Programs for Improving Shared Decision Making and the Person's Experience in Mental Health Care

UPMC Center for High ValueHealth Care
| Pennsylvania
Kim MacDonald-Wilson, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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